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We support discovery research into life, health and wellbeing, and we’re taking on three worldwide health challenges: mental health, infectious disease and climate and health.Learn more about what we doFind funding opportunitiesLog in to Wellcome FundingRead funding guidance
[H2] Latest content
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[H3] World’s largest global prize for mental health science launches
14 May 20262-minute readA new scientific prize, the Wellcome Prize for Mental Health Science with Nature, will celebrate breakthrough interventions for depression, anxiety and psychosis that deliver real benefits to the people who need them, with a $1 million prize.ReportReport
[H3] Britain talks trust in science
17 April 2026Expert perspectivesAuthorProfessor Jason Kai Wei Lee Expert perspectivesAuthorProfessor Jason Kai Wei Lee
[H3] How can cities adapt to protect our health from extreme heat?
7 April 20264-minute readNewsNews
[H3] Mental health tool, which includes Tetris, stops intrusive flashbacks
19 February 20265-minute readWellcome in numbers Our work in the year 2024/25£1.91.9 billion british poundsbillionOur charitable expenditure, supporting science to solve the urgent health challenges facing everyone.2,7232723 active grantsactive grantsacross 133 countries, with a total value of £7.3 billion.403,000403000 visitorsvisitorsto the Wellcome Collection, our free museum and library in London.
[H3] When Science Finds a Way
Our podcast is back with a fourth season, uncovering more incredible stories of how scientists and communities are tackling the urgent health challenges of our time.
[H2] Other homepage CTAs
[H3] About us
Learn about our teams, our strategy and how we are funded.
[H3] Wellcome Collection
Wellcome Collection is our free museum exploring health and human experience.
[H3] Wellcome Photography Prize
Celebrating compelling imagery that captures stories of health, science and human experience.

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[H2] Our history
We were founded in 1936 after the death of Sir Henry Wellcome, a pharmaceutical entrepreneur, with a pioneering approach to drug design.In his will, he left us three important things: his wealth; his collection of historical medical items; and our mission to improve health through research.Since our formation, we have supported breakthroughs in scientific discoveries and advocated for policies to improve health for everyone.Today, Wellcome supports science to solve the urgent health challenges facing everyone. We have four programmes of work: one for discovery research, and three to find solutions for the challenges of mental health, climate and health, and infectious diseases.
[H3] Explore the timeline giving you a snapshot of key achievements since 1936
[H3] Highlights of our activities since 1936
1936Wellcome Trust was founded after the death of Sir Henry Wellcome.1938First grants were made by the Wellcome Trust to support Henry Wellcome’s mission for the Trust, to improve health through research.1955Wellcome established the Wellcome Research Travel Grants scheme, the first funding in the UK for university researchers to make short visits to other laboratories around the world.1957Wellcome provided £100,000 to build Wellcome Institute for Research on Foot-and-Mouth Disease in Cattle in Nairobi, Kenya.1967Wellcome trustees adopted a more proactive funding policy. As well as responsive-mode grants, they looked for opportunities to fill gaps and create opportunities to advance research.1979To support research in Thailand and Laos, Wellcome established the Wellcome Trust-Mahidol University-Oxford Tropical Medicine Research Programme in partnership with the Faculty of Tropical Medicine, Mahidol University.1989The KEMRI-Wellcome Trust Research Programme was established in partnership with the Kenya Medical Research Institute. 1990Wellcome joined the Human Genome Project, the largest international collaboration ever undertaken in biology. Over 13 years, thousands of scientists around the world sequenced the 3 billion pieces of genetic information in every human cell (except red blood cells).Learn more1991Wellcome supported the creation of the Oxford University Clinical Research Unit (OUCRU), a large-scale clinical and public health research unit with site offices in Vietnam, Indonesia and Nepal.1992The Wellcome Sanger Institute was established to complete one-sixth of the total sequencing for one of the most ambitious projects ever attempted in biology: sequencing the human genome.1995The Malawi-Liverpool-Wellcome Trust Clinical Research Programme was established to use science to drive health and wellbeing in Malawi. 2003Nearly a third of the Human Genome Project was sequenced at the Wellcome Sanger Institute. New knowledge and tools stemming from the project are now transforming healthcare, such as through better diagnosis of rare genetic disorders.2007Wellcome Collection, our museum and library, opened in London, UK.Learn more2010Wellcome signed an agreement between the Medical Research Council, Cancer Research UK and University College London to found The Francis Crick Institute which would go on to become the largest biomedical research institute in Europe.2014In response to the biggest ever outbreak of Ebola virus, Wellcome led a fast, coordinated programme of research. These efforts contributed to the first Ebola vaccine being licensed and approved in 2019.Learn more2017Wellcome was a founding member of the Coalition for Epidemic Preparedness Innovations (CEPI), which funded nine Covid-19 vaccines.2020Wellcome Leap was established with a $250mn investment from Wellcome, to support scientists, technologists and innovators from around the world to pursue bold ideas that would fall outside the remit of conventional life sciences funding.Learn more2022Wellcome and the Bill & Melinda Gates Foundation pledged $150 million each to the Coalition for Epidemic Preparedness Innovations (CEPI) to help end the Covid-19 pandemic and prevent another major outbreak.Learn more2023The UN’s annual Climate Change Conference (COP) included a Health Day for the first time.Milestone 1 of 19PrevNextRead more about our history
[H2] What we stand for
[H3] Wellcome's vision and strategy
We want a healthier future for everyone. That’s why we support science to solve urgent health challenges facing everyone.Our perspective on health and how to improve it spans science, innovation, and society.  We aim to enable transformative shifts in understanding life, health and wellbeing, and equitable health solutions that work for people who need and want them.
[H3] Our beliefs and values
Our beliefs provide the focus for our strategy, policy and funding decisions. Our values guide how we behave, work and lead – both individually and as an organisation.Read our beliefs and values
[H3] Better health for all
Wellcome’s vision is a healthier future for everyone. Equity is vital to our mission, and part of all we do.Read about how we're driving equitable health outcomes
[H3] Positions and statements
To support the research and development ecosystem, we also engage with issues relevant to our role as a global charitable foundation.Read our positions and statements
[H2] How we're funded
[H3] Investments
We are an independent charitable foundation. Our work is funded from an investment portfolio that currently stands at £39.9 billion.We use the returns from our investments to fund our work.
[H2] Working here
[H3] Our people
[H3] Our governance
[H3] Work with us
[H2] Contact us
[H3] General or funding enquiries
Find information on how to contact us, directions to our offices, and information about accessibility in our buildings.Get in touch
[H3] Media queries
Our media office helps journalists interested in Wellcome and Wellcome Collection activities.Contact the media office
[H2] More about Wellcome
[H3] Our priorities
[H3] Engagement and advocacy
[H3] Research funding

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Share with EmailShare with LinkedInShare with BlueskyShare with XShare with FacebookScience is always adding to our knowledge of human health, but how do ideas become breakthroughs, and how can those breakthroughs bring about a better world? Could mosquitos help prevent disease? Will AI tools transform mental healthcare? How is a once-ignored drug now being used to save lives? And what can science do to keep us healthy as we age? Join botanist-turned-Hollywood actor Alisha Wainwright as she meets the scientists, innovators, and communities searching for solutions to our biggest health challenges. Listen to When Science Finds a WayPressing play on the video above will set a third-party cookie. Please read our cookie policy for more information.
[H3] Expand to read the transcriptShow
Alisha Wainright: On the new season of When Science Finds a Way…Haleema Shakur-still: We went in believing something and the result shocked us into learning even more.Tom Grylls: I think one way to put it is, it's like the emergency brake that we can pull on climate change.Miranda Wolpert: The potential for AI to scale interventions, to be able to reach millions of people across the world, is enormous.Alisha Wainright: When Science Finds a Way, from Wellcome. Find season 4 wherever you get your podcasts.
[H2] Episodes
[H3] Season Four
Transcripts are available for all episodes. New episodes are released weekly.Podcast
[H3] Episode 7: How can we respond to extreme heat and its effect on mental health?​
20 May 2026Extreme heat is becoming more common around the world. While its physical dangers are well known, scientists are only beginning to understand its effects on mental health. Host Alisha Wainwright explores the growing research linking rising temperatures and mental wellbeing. PodcastPodcast
[H3] Episode 6: We're living longer, but are we living healthier?
13 May 2026People around the world are living longer than ever before. But how can we ensure those extra years are healthy ones? Host Alisha Wainwright explores the science of ageing and how growing knowledge could lead to more personalised approaches. PodcastPodcast
[H3] Episode 5: Does the food we eat improve our mental health?
6 May 2026We often think about food in terms of physical health. But what role could diet play in mental wellbeing? Host Alisha Wainwright explores the science linking nutrition and mental health. PodcastPodcast
[H3] Episode 4: Why was a life saving drug overlooked for half a century?
29 April 2026Postpartum haemorrhage is one of the leading causes of maternal death worldwide. But an overlooked drug is helping change that. Host Alisha Wainwright explores the story of tranexamic acid (TXA) and how it is now saving thousands of lives after childbirth. PodcastPodcast
[H3] Episode 3: What happens when fungi find their way into our brains?
22 April 2026Brain invading fungi might sound like science fiction, but they are a real-world health threat. Host Alisha Wainwright explores Cryptococcal meningitis, the leading cause of death from fungal disease worldwide.PodcastPodcast
[H3] Episode 2: AI and mental health - can we trust AI therapy?
15 April 2026AI chatbots and apps are increasingly being used for mental health support. But could these new tools carry hidden risks? Host Alisha Wainwright continues her exploration of AI and mental health, looking at how to stay safe when seeking help digitally and the challenges posed by unregulated tools. PodcastPodcast
[H3] Episode 1: AI and mental health - could AI transform access to care?
8 April 2026Artificial intelligence is starting to reshape mental health care. Host Alisha Wainwright explores how researchers are using AI to better understand patients’ needs and support treatment decisions.
[H3] Season three
PodcastPodcast
[H3] Episode 7: Vaccine equity – searching for a cure
22 October 2025The Covid-19 pandemic exposed a deep inequality: Africa manufactured less than 1% of the vaccines it used. But efforts to change that are accelerating. Alisha speaks with Dr Delese Mimi Darko about the rise of vaccine manufacturing across the continent, and with the team at Biovac in South Africa, developing an Oral Cholera Vaccine with end-to-end production in sight. It’s a powerful story of collaboration, innovation, and the urgent drive for equity in global health. PodcastPodcast
[H3] Episode 6: Food for thought – eating our way to a sustainable future
15 October 2025Alisha meets Professor Pete Scarborough and Jo, a participant testing a new digital tool to support sustainable food choices. Together, they explore how science and technology can help us navigate the complexities of global diets, and make healthier, climate-friendly eating possible worldwide. PodcastPodcast
[H3] Episode 5: Problem-solving therapy – the answer to youth depression?
8 October 2025Young people face a growing mental health crisis, but effective treatments remain limited. Alisha and Professor Vikram Patel explore a school-based trial in India testing POD (Problem Identification, Option generation and Do it), a practical approach helping students tackle problems head-on. With counsellor Bindiya Chodankar and researchers adapting the model for universities, this episode asks: can simple, accessible tools reshape youth mental health? PodcastPodcast
[H3] Episode 4: Zooming in – particle physics and the future of medical imaging
1 October 2025Hierarchical Phase Contrast Tomography (HiP-CT) is a new imaging technology that allows entire human organs to be scanned in 3D, in unprecedented detail. Alisha speaks with the researchers who pioneered this innovation, uncovering what it revealed about Covid-19 and what it could mean for the future of medicine. PodcastPodcast
[H3] Episode 3: Early warning systems – using tech to predict disease outbreaks
24 September 2025From malaria to dengue, climate change is reshaping patterns of infectious disease. But could the same data that tracks our warming planet help prevent future outbreaks? Alisha meets researchers using climate models and local insights to map where diseases are likely to spread, turning prediction into a powerful tool for global health.PodcastPodcast
[H3] Episode 2: Inclusive research – autism from menstruation to menopause
17 September 2025Alisha speaks with Dr Aimee Grant about ‘Autism: from Menstruation to Menopause’, a groundbreaking study led entirely by autistic people. With input from a neurodivergent Community Council, the project is gathering vital data across the reproductive life cycle to design tools that make healthcare more inclusive and accessible.PodcastPodcast
[H3] Episode 1: The arts – can creativity help mental health?
10 September 2025From singing to painting, creative outlets have long been linked to better mental health. But how can we harness their therapeutic power in practice? Alisha meets Professor Daisy Fancourt, whose research is establishing the arts as a key ingredient for wellbeing, alongside diet and exercise.
[H3] Season two
PodcastPodcast
[H3] Episode 8: AVATAR Therapy – digital dialogues for mental health
14 May 2025Hearing voices is a challenging symptom of psychosis that treatments have often failed to address effectively. AVATAR therapy is a remarkable approach that could help patients engage with distressing voices and regain control. Alisha meets Dr Vaughan Bell to explore the therapy's potential, talk about findings from the latest clinical trial and hear a personal story of transformation.PodcastPodcast
[H3] Episode 7: Decoding cancer – how genomics is transforming treatment
7 May 2025Genomics has revolutionised cancer research, offering new hope for cancer diagnosis and treatment. But there are challenges ahead. Alisha is joined by Dr Peter Campbell and researchers Dr Solomon Rotimi and Sara Gómez Trillos to discuss the breakthroughs and the issue of ensuring fair access to advancements for patients worldwide.PodcastPodcast
[H3] Episode 6: Combating cholera – can technology really turn the tide?
30 April 2025Alisha sits down with Professor Iruka Okeke to talk about the factors driving cholera's spread and the innovative mapping techniques being used in Kenya to identify hotspots.PodcastPodcast
[H3] Episode 5: Pregnancy and research – inclusion in vaccine trials
23 April 2025Alisha is joined by Dr Flor M Munoz, a global expert in maternal immunisation to discuss a new vaccine trial, safety considerations and the future.PodcastPodcast
[H3] Episode 4: Cool roofs – homes fit for a hotter world
16 April 2025As rising temperatures challenge vulnerable regions, could ‘cool roofs’ be the affordable, sustainable solution? Alisha joins Dr Aditi Bunker to talk about the remarkable health benefits uncovered in Burkina Faso's trial. Hear firsthand accounts of how this simple intervention significantly reduces indoor temperatures, lowers heart rates and improves overall health.PodcastPodcast
[H3] Episode 3: Working it out – exercise, the brain and mental health
9 April 2025Alisha meets Dr Jonathan Roiser and his team of researchers to uncover insights from a groundbreaking pilot study exploring brain activity during exercise, including how it could transform the diagnosis and treatment of conditions like depression.PodcastPodcast
[H3] Episode 2: Cultural burning – could traditional practices prevent modern wildfires?
2 April 2025Join Alisha and Dr Nicole Redvers as they explore cultural burning, a traditional Indigenous technique offering a potential solution to modern wildfire challenges. Hear from those bridging traditional practice and science.PodcastPodcast
[H3] Episode 1: From risk to remedy – how mosquitoes could save lives
2 April 2025Travel to Colombia to hear how Professor Scott O’Neill, founder of the World Mosquito Program, is using mosquitoes infected with a naturally occurring bacterium. It's part of a game-changing approach that’s revolutionising disease prevention.
[H3] Season one
PodcastPodcast
[H3] Episode 13: What does the future hold for global health?
30 August 2023Join Julia Gillard, Chair of Wellcome, as she brings together three experts from the podcast series to reflect on the main themes that have emerged and ask what challenges still lie ahead in the field of global health.PodcastPodcast
[H3] Episode 12: Will genomic sequencing prevent future pandemics?
30 August 2023Alisha speaks to Professor Christian Happi about his pioneering use of genomic sequencing during the 2014 Ebola outbreak in Nigeria, and how the technology could unlock the secrets of disease prevention.PodcastPodcast
[H3] Episode 11: Should we give out cash to improve mental health?
23 August 2023Alisha speaks to Professor Vikram Patel to explore how cash transfers could hold the key to coming up with a universally applicable and low-cost breakthrough in the treatment of mental health disorders.PodcastPodcast
[H3] Episode 10: How can we feed the world with a changing climate?
16 August 2023Alisha speaks to Professor Ruth DeFries to discuss how the world has become reliant on a small number of crops (such as corn and rice), leaving us in a vulnerable position if these staples do not grow well as the planet heats.PodcastPodcast
[H3] Episode 9: How can sleep impact on mental health?
9 August 2023Alisha speaks to Professor Daniel Freeman about the importance of sleep and its potential in fighting the global mental health crisis.PodcastPodcast
[H3] Episode 8: One scientist’s journey to respecting indigenous customs
2 August 2023Danish geneticist Professor Eske Willerslev and Dr Shane Doyle, a member of the Crow Tribe in Montana, USA, join Alisha to discuss the possibilities and pitfalls of ancient DNA research and how to build mutual trust and respect between indigenous communities and scientists.PodcastPodcast
[H3] Episode 7: How can volunteering to be infected save lives?
26 July 2023Human infection studies are a quick and effective way to gather data to see whether or not a vaccine is working. Alisha speaks with Dr Dingase Dula to learn more about the impact of infection studies in combating infectious disease.PodcastPodcast
[H3] Episode 6: How can we revitalize informal settlements?
19 July 2023Around the world, roughly one billion people live in informal settlements. These communities are especially vulnerable to extreme weather events. Alisha speaks to Professor Karin Leder about projects in Indonesia and Fiji that are collaborating with local communities to address these challenges.PodcastPodcast
[H3] Episode 5: Can new technology help predict psychosis?
12 July 2023Alisha is in discussion with Professor Iris Sommer to understand more about psychosis – one of the most severe and stigmatised mental health conditions – and hear about an innovative AI project that could help us spot the signs early on.PodcastPodcast
[H3] Episode 4: Can a research study change a city?
5 July 2023Alisha talks to Professor John Wright about how one open-ended study of 40,000 people in the city of Bradford is changing lives and bonding communities around the world.PodcastPodcast
[H3] Episode 3: How can we work on a heating planet?
28 June 2023Kathy Baughman McLeod talks Alisha through the realities of what heat stress does to us, how workers across the globe are feeling the heat, and the tangible solutions being implemented to increase resilience.PodcastPodcast
[H3] Episode 2: How is research helping the fight for equality?
28 June 2023Professor Susan Golombok joins Alisha to discuss how her research into different family structures has changed laws and perceptions on same-sex parenting.PodcastPodcast
[H3] Episode 1: What can we do to stop superbugs?
28 March 2023Dr Anand Anandkumar joins Alisha to correct the misconceptions around antimicrobial resistance and explain what we can do about it.
[H2] Transcripts
Transcripts are available to download for all episodes.
[H3] Season four
Episode 7: How can we respond to extreme heat and its effect on mental health?​PDF 175.7 KBEpisode 6: We're living longer, but are we living healthier?PDF 155.3 KBEpisode 5: Does the food we eat improve our mental health?PDF 184.5 KBEpisode 4: Why was a life saving drug overlooked for half a century?PDF 168.1 KBEpisode 3: What happens when fungi find their way into our brains?PDF 174.1 KBEpisode 2: AI and mental health: can we trust AI therapy?PDF 154.2 KBEpisode 1: AI and mental health: could AI transform access to care?PDF 135.1 KB
[H3] Season three
Episode 7: Vaccine equity – searching for a curePDF 162.7 KBEpisode 6: Food for thought – eating our way to a sustainable futurePDF 219.8 KBEpisode 5: Problem-solving therapy – the answer to youth depression? PDF 193.8 KBEpisode 4: Zooming in – particle physics and the future of medical imaging PDF 212.7 KBEpisode 3: Early warning systems – using tech to predict disease outbreaksPDF 199.5 KBEpisode 2: Inclusive research – autism from menstruation to menopausePDF 217.6 KBEpisode 1: The arts

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