Training Example: Synthroid (AbbVie Inc.) – Review the Data, Give Your Score & Compare to the Real AI Evaluation

Precise. Consistent. Trusted.
[H1] MAKE SURE IT'S SYNTHROID
America’s #1 prescribed branded hypothyroidism medication*
*February 2019 through January 2025.
Tablets shown not actual size and may not represent exact color.

Precise. Consistent. Trusted.
[H1] MAKE SURE IT'S SYNTHROID
America’s #1 prescribed branded hypothyroidism medication*
*February 2019 through January 2025.
Tablets shown not actual size and may not represent exact color.

Dosing tailored 
to you
There's no "one-size-fits-all" solution for hypothyroidism. That's why Synthroid comes in 12 precise dosing options, so you and your doctor can find the dose that's right for you.

See why precision matters

Voice your choice for Synthroid
Discover simple ways to make sure you receive brand-name Synthroid exactly as your doctor prescribed at the pharmacy.

How to make sure it’s Synthroid

Looking for ways to save?
With multiple ways to save on Synthroid, you can find the savings benefit that works to help you get your prescription.

Learn how to start saving

[H2] Help us guide you
Answer the question below for content that’s customized just for you.

Which of the following best describes you or your loved one?

I am not diagnosed with hypothyroidism
I have been diagnosed with hypothyroidism
I am currently taking Synthroid

Your answer: I am not diagnosed with hypothyroidism
Learn more about how Synthroid treats hypothyroidism
Understand how Synthroid works
Hear what real patients have to say about Synthroid
Watch Synthroid stories

Your answer: I have been diagnosed with hypothyroidism
Can the precise, tailored treatment of Synthroid help you?
Learn about dosing
Do you know all the ways you can save on Synthroid?
Learn how to save

Your answer: I am currently taking Synthroid
Do you know all the ways you can save on Synthroid?
Learn how to save
Do you know how to make sure you’re getting Synthroid at the pharmacy?
Make sure it’s Synthroid

Change answer

[H2] Real Synthroid stories
[H3] Managing hypothyroidism: Lisa’s story
Hear about how Lisa works closely with her doctor to manage her hypothyroidism with Synthroid, a treatment she’s able to easily work into her regular routine.

[H3]

Transcript

Transcript

A SYNTHROID Story: Meet Lisa
ON SCREEN:
Lisa
Living with hypothyroidism
LISA:
Hi, I'm Lisa. I'm a wife and mother of three amazing boys. And I adore my corgi, Mabel.
In my spare time, I love listening to music, I love to restore furniture, and my real passion is writing.
In the fall of 2008, after a routine physical and a series of tests, I was diagnosed with thyroid cancer. That led to meeting with a surgeon, who had to remove my entire thyroid gland. This led to me living with hypothyroidism for the rest of my life.
After my surgery, I met with my endocrinologist, and he taught me all about living with hypothyroidism and that I would have to take, every single day, a thyroid hormone replacement medication. And he prescribed to me, SYNTHROID.
ON SCREEN:
Individual results may vary.
Talk to your doctor to determine which medication is right for you.
LISA:
He told me it would take a while to get the right dosage for me, and that over time, adjustments might need to be made with the amount of SYNTHROID that I would be taking on a daily basis.
ON SCREEN:
Your doctor will carefully monitor your thyroid levels regularly.
Individual results may vary.
LISA:
I've had several different doses over the past almost 16 years. You really have to advocate for yourself, and you have to keep the communication going with your endocrinologist, and be on top of your health, because things happen in life, and sometimes that medicine just needs to be adjusted.
ON SCREEN:
Your doctor will regularly check your TSH blood levels.
LISA:
My doctor told me that I would have to take my medication in the morning, first thing, on an empty stomach, with water, and that I would have to wait about an hour before I had breakfast.
ON SCREEN:
SYNTHROID should be taken alone, with water ONLY, on an empty stomach 30 minutes to 1 hour before breakfast.
LISA:
When I get up in the morning, I take my SYNTHROID first thing, and it's become a routine. I look forward to actually taking that medicine every morning ‘cause that's how I start my day.
Even my dog knows now, like, she'll hear me with the pill bottle. I get up, take my SYNTHROID, and then it's time to go for a walk. So it has to become part of your life, has to become part of your daily routine.
One important thing I have learned over the years is that there are certain foods that can interfere with the absorption of SYNTHROID. So that’s why it’s important to take it only with water.
My doctor also pointed out to me, which I found very interesting, to wait ‘til nighttime to take my calcium supplements and any other vitamins that I do take.
When he writes my prescription, he specifically states SYNTHROID.
ON SCREEN:
The Food and Drug Administration has determined that certain levothyroxine products are interchangeable.
LISA:
I have a terrific relationship with my endocrinologist. Not only because I see him at least four times a year, but it's not just about the treatment. He asks me how I'm doing, how my family is, we just get along really well and he sincerely cares. It’s so important to see that personal side of a physician ‘cause they have it. It's not all clinical and black and white.
They just want to help us. And you have to really nurture that relationship.
If there's one thing I've learned over the past 16 years, it's to listen to my body, because it is telling me when something's just not right and when something needs to be adjusted with my thyroid hormone replacement medication. It's so critical. And it is the answer. It's the key. You have to listen to your body, and you have to communicate with your doctor.
It's been so long that I don't even really think about it anymore. And when my levels are in check and I'm taking my medicine every single day, I feel good. I can move on with life.
LISA:
Knowing that my treatment is consistent gives me confidence.
ON SCREEN:
SYNTHROID is not for everyone.
I need SYNTHROID every day. And thank goodness it's around, because it's going to keep me going, and I'm very fortunate.

Hear what other patients are saying

[H3] The Synthroid assurance
Synthroid tablets contain no ingredients made from gluten-containing grain (wheat, barley, or rye).

[H3] Questions about Synthroid? We've got answers.
Learn about Synthroid, hypothyroidism, and more.

Explore FAQs

[H3] Use
SYNTHROID® (levothyroxine sodium) tablets, for oral use is a prescription, man-made thyroid hormone that is used to treat a condition called hypothyroidism in adults and children, including infants. It is meant to replace a hormone that is usually made by your thyroid gland. Generally, thyroid replacement treatment is to be taken for life. SYNTHROID should not be used to treat noncancerous growths or enlargement of the thyroid in patients with normal iodine levels, or in cases of temporary hypothyroidism caused by inflammation of the thyroid gland (thyroiditis).

[H3] Important Safety Information
Thyroid hormones, including SYNTHROID, should not be used either alone or in combination with other drugs for the treatment of obesity or weight loss. In patients with normal thyroid levels, doses of SYNTHROID used daily for hormone replacement are not helpful for weight loss. Larger doses may result in serious or even life-threatening events, especially when used in combination with certain other drugs used to reduce appetite.
Do not use SYNTHROID if you have uncorrected adrenal problems.
Use SYNTHROID only as ordered by your doctor. Taking too much or too little SYNTHROID may lead to negative effects on growth and development, heart function, bone health, reproductive function, mental health, digestive function, and changes in blood sugar and cholesterol metabolism in adult or pediatric patients.
Taking too much levothyroxine may affect your heart, especially if you are elderly or have heart disease. Tell your doctor immediately if you have any signs of increased heart rate, chest pain, or an irregular heartbeat.
Tell your doctor about any other medical conditions you may have, especially heart disease, diabetes, blood clotting problems, and adrenal or pituitary gland problems. The dose of other drugs you may be taking to control these conditions may have to be changed while you are taking SYNTHROID. If you have diabetes, check your blood sugar levels and/or the glucose in your urine, as ordered by your doctor, and immediately tell your doctor if there are any changes. If you are taking blood thinners, your blood clotting status should be checked often.
Taking too much levothyroxine has been associated with increased bone loss, especially in women after menopause.
Tell your doctor if you are pregnant or breastfeeding or are thinking of becoming pregnant while taking SYNTHROID. Your dose of SYNTHROID may need to be increased during your pregnancy.
Tell your doctor if you start experiencing any of the following symptoms: rapid or abnormal heartbeat, chest pain, difficulty catching your breath, leg cramps, headache, nervousness, irritability, sleeplessness, shaking, change in appetite, weight gain or loss, vomiting, diarrhea, increased sweating, difficulty tolerating heat, fever, changes in menstrual periods, swollen red bumps on the skin (hives) or skin rash, or any other unusual medical event.
Partial hair loss may occur during the first few months you are taking SYNTHROID.
Tell your doctor if you are taking any other drugs, including prescription and over-the-counter products.
Products such as iron and calcium supplements and antacids can lower your body’s ability to absorb levothyroxine, so SYNTHROID should be taken 4 hours before or after taking these products.
Tell your doctor or dentist that you are taking SYNTHROID before any surgery.
Use SYNTHROID only as ordered by your doctor. Take SYNTHROID as a single dose, preferably on an empty stomach, one-half to one hour before breakfast.
Once your doctor has found your specific SYNTHROID dose, it is important to have periodic lab tests and clinical evaluations to assess your treatment response.
Foods like soybean flour, cottonseed meal, walnuts, and dietary fiber may cause your body to absorb less SYNTHROID from the gastrointestinal tract. Grapefruit juice may cause your body to absorb less levothyroxine and may reduce its effect. Let your doctor know if you eat these foods, as your dose of SYNTHROID may need to be adjusted.
It may take several weeks before you notice an improvement in your symptoms.
This is the most important safety information you should know about SYNTHROID. For more information, talk with your doctor.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.
US-SYNT-220158

[H2] You are leaving the Synthroid.com consumer site
You are about to enter a site that is for US Healthcare Professionals only. By selecting “Yes” below, you certify that you are a healthcare professional and that you wish to proceed to the Healthcare Professionals Only section of this site. Products or treatments described on this site are available in the US but may not be available in all other countries.
I am a licensed healthcare professional and wish to proceed to the Healthcare Professionals Only section of this site.

Yes

No

[H2] You are now leaving an AbbVie website
You are leaving an AbbVie website and connecting to a site that is not under the control of AbbVie. AbbVie is not responsible for the contents of any such site or any further links from such site. AbbVie is providing these links to you only as a convenience, and the inclusion of any link does not imply the endorsement of the linked site by AbbVie. You should also be aware that the linked site may be governed by its own set of terms and conditions and privacy policy for which AbbVie has no responsibility.
Conversely, the presence of this link does not imply the linked site's endorsement of Synthroid.com or AbbVie.
Do you wish to leave this site?

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No

[H2] Synthroid Copay Full Terms and Conditions
Terms and Conditions apply. This benefit covers SYNTHROID® (levothyroxine sodium). Eligibility: Available only to patients with commercial insurance coverage for SYNTHROID who meet eligibility criteria. The form of co-pay assistance, enrollment requirements, and processes may vary, please call 1-866-627-4980 for additional information. Co-pay assistance program is not available to patients receiving reimbursement under any federal, state, or government-funded insurance programs (for example, Medicare [including Part D], Medicare Advantage, Medigap, Medicaid, TRICARE, Department of Defense, or Veterans Affairs programs) or where prohibited by law or by the patient’s health insurance provider. If you live or receive treatment in certain states, you may not be eligible. If at any time a patient begins receiving drug coverage under any such federal, state, or government-funded healthcare program, patient will no longer be able to use the SYNTHROID Co-pay Savings Card and patient must call 1-866-627-4980 to stop participation. Co-pay assistance provided under this program is offered to and intended for the sole benefit of eligible patients and may not be transferred to or utilized for the benefit of third parties, including, without limitation, third-party insurance plans and/or pharmacy benefit managers and their agents. Patients may not seek reimbursement for value received from the SYNTHROID Co-pay Savings Program from any third-party payers, including insurance plans, flexible spending plans or health savings accounts. Co-pay support made available under this program may not be used with any other coupon, discount, prescription savings card, free trial, or other offer (including any program offered by a third-party insurance plan or pharmacy benefit manager, or an agent of either, that adjusts patie

[H1] Taking Synthroid Tips to help you stay on track with your treatment
How you take Synthroid matters. Explore the tabs below to find everything from factors your doctor will consider when choosing your starting dose, to what you can expect long term. As always, be sure to follow up with your doctor on any questions you may have at your next appointment.

Starting on Synthroid
Starting on Synthroid

Making sure it’s Synthroid
Making sure it’s Synthroid

Continuing on Synthroid
Continuing on Synthroid

[H2] Precise dosing matters
There's no one dose that's right for all people with hypothyroidism. That's why Synthroid comes in a variety of dosing strengths to match each person's exact needs.

[H2] Dosing options to fit your needs
Synthroid comes in 12 dosing options to help your doctor find the dose that's right for you. Your doctor will determine your starting dose based on your weight, age, cause of hypothyroidism, and other health conditions, as well as other medications you’re taking.
Tablets shown not actual size and may not represent exact color.

[H3] Real Synthroid stories
Finding the right dose
Hear the steps Wendy took to make sure she found the right doctor—and the right dose.

[H3]

Transcript

Transcript

Finding the right dose
ON SCREEN:
WENDY, DIAGNOSED WITH HYPOTHYROIDISM
WENDY:
My process of finding the right dose included several different doctors actually. They just were having a very difficult time dialing in appropriate levels. Hypothyroidism can actually cause a great deal of complications in pregnancy, so it was important to have it correct. I went through about three endocrinologists. I think it’s utterly critical you find an endocrinologist that you have a rapport with, you have a connection with. Gratefully, my endocrinologist has had my thyroid medication dialed in and under control. I absolutely love him.
ON SCREEN:
YOUR DOCTOR WILL CAREFULLY MONITOR YOUR THYROID LEVELS REGULARLY. INDIVIDUAL RESULTS MAY VARY.
WENDY:
If I were to meet somebody just starting on this journey, my advice to them is find a doctor they have an excellent rapport with and don’t settle for less. I have a very happy life while living with hypothyroidism. I trust Synthroid to keep my thyroid level exactly where it needs to be.
ON SCREEN:
SYNTHROID IS NOT FOR EVERYONE. TALK TO YOUR DOCTOR TO DETERMINE WHICH MEDICATION IS RIGHT FOR YOU.
ON SCREEN:
SYNTHROID is not right for everyone. Talk to your doctor to determine which medication is right for you.
ON SCREEN:
TO SEE WENDY’S FULL STORY, VISIT THE “SYNTHROID STORIES” SECTION OF SYNTHROID.COM

Hear what other patients are saying

What to expect when starting Synthroid
When you first start taking Synthroid, your doctor will usually test your TSH levels every 6 to 8 weeks. Because your thyroid hormone needs are very precise, your doctor may need to make small adjustments to find the dose that’s right for you.
It may take several weeks before you notice Synthroid is working and for your thyroid hormone levels to adjust to the correct range.

[H2] How to take Synthroid the right way, every day
The way you take Synthroid can affect how much medicine your body is getting. That's why it's critical to take Synthroid as your doctor prescribes, and to take it the same way, every day.
Remember these quick tips on how to take Synthroid:

Once a day
Take Synthroid once a day, every day, at the same time before breakfast.

On an empty stomach
Only take Synthroid with water and on an empty stomach.

Wait 30 minutes
Wait 30 minutes to 1 hour before eating or drinking anything other than water.

[H3] Stay on track with your treatment
Keep this cheat sheet handy for fast facts about Synthroid and how to take it the right way.

Download cheat sheet

[H2] Myths vs Facts

It may take time to find the proper dose of Synthroid that restores your thyroid hormone levels. What do you think, is this a myth or a fact?

Myth
Fact

Sorry, that's incorrect. This is a fact.
It may take time to find the proper dose of Synthroid that restores your thyroid hormone levels.
It may take up to several weeks for you and your doctor to find the dose of Synthroid that works best for you. Then, after finding the right dose, it’s up to you to take your Synthroid the right way, every day, so that it can work properly. You can review how to take Synthroid here.
See more myths vs facts

Correct! This is a fact.
It may take time to find the proper dose of Synthroid that restores your thyroid hormone levels.
It may take up to several weeks for you and your doctor to find the dose of Synthroid that works best for you. Then, after finding the right dose, it’s up to you to take your Synthroid the right way, every day, so that it can work properly. You can review how to take Synthroid here.
See more myths vs facts

Hide the Answer

[H3] Perfecting your Synthroid routine
Establish your dosing routine to help you remember to take Synthroid the same way, every day.
Here are a few helpful suggestions:
Keep Synthroid in sightKeep Synthroid beside something you see or use when you wake up in the morning. It could be by your phone, toothbrush, or keys.
Stick a note where you’ll see itIf you walk your dog every morning, place a sticky note near the leash. If you read the morning news on your smartphone or tablet, place a sticky note on it.
Map out your medication scheduleUse a weekly pillbox to help you plan timing for your medication and avoid dosing errors.
Remember when you’ve taken Synthroid
Turn your medicine bottle or weekly pillbox upside down after you take Synthroid. Before going to sleep, turn your bottle right side up so you know to take Synthroid in the morning.
Never miss a dose
You can also sign up to get daily reminders via text or email to take your Synthroid.
Looking to take advantage of these helpful reminder tools?

Sign up now

[H2] Remember: Avoid these foods and supplements

Foods that interfere with Synthroid
Foods containing soy and cottonseed meal can make Synthroid less effective. Walnuts, grapefruit juice, and dietary fiber can also make Synthroid less effective. If you eat any of these on a regular basis, check with your doctor. They may need to adjust your dose of Synthroid.

Supplements that interfere with Synthroid
Some supplements and medications can also interfere with the way Synthroid works. To avoid this, you should take Synthroid 4 hours before or after taking:
Iron supplements or multivitamins with iron
Calcium supplements or multivitamins with calcium
Antacids
Biotin/vitamin B7 (discontinue use at least 48 hours before any thyroid-function tests your doctor may want to administer)

[H2] Commonly asked questions

What's the best time of day to take Synthroid?

You should always take Synthroid at the same time every day. Ideally, it's preferable to take Synthroid 30-60 minutes before you eat breakfast in the morning to ensure the synthetic thyroid hormone is digested and absorbed into your body without interference from food or supplements.

What should I do if I’m traveling to another time zone?

Even if you’re traveling to another time zone, it's important to maintain your dosing schedule by taking Synthroid at the same time every day.

What should I do if I miss a dose?

If a dose is missed in the morning, try to take it as soon as possible. If it’s been over a day since your last dose, skip the missed dose and take your next normal dose as scheduled. Never take more than your prescribed dose.

[H3] Are you sure you're taking Synthroid?
Many people who think they're taking Synthroid might actually be taking a generic.

How to make sure it's Synthroid

[H2] How to make sure it’s Synthroid
Did you know: 1 out of every 3 people who think they’re taking Synthroid aren’t
Although your doctor may have prescribed Synthroid in some cases it can be switched to a generic brand at the pharmacy without you even realizing it.
That’s because some generics come in the same shapes, colors, and doses as Synthroid.
The Food and Drug Administration has determined that certain levothyroxine products are interchangeable and can be substituted at the pharmacy.

[H2] Make sure you’re getting what your doctor prescribed
You worked closely with your doctor to find the dose of Synthroid that’s right for you, so if your doctor prefers for you to stay on Synthroid, here are ways to make sure you get brand name Synthroid.

Enroll in the Synthroid Delivers Program
To make it even simpler to make sure you always get Synthroid, enroll in the Synthroid Delivers Program and have Synthroid delivered right to your door for only $25 a month for a 90-day prescription.*
*Other pricing available for 30 days ($29.50) and 60 days ($54). See full pricing information. Terms, conditions, and eligibility restrictions apply.

Ask your doctor to note their preference on your prescription
Without specific instructions for the pharmacy, such as DAW or “Dispense As Written,” you may get switched to another treatment without your knowledge, depending on your state’s pharmacy laws.

Inform your pharmacist
Always let your pharmacist or mail-order pharmacy know that you and your doctor prefer brand-name Synthroid.

Check your pills
Before leaving the pharmacy (or as soon as your prescription arrives in the mail), check the pill to ensure it says “SYNTHROID.” If it doesn’t, let your pharmacist know what you and your doctor prefer.

[H3] Real Synthroid stories
Making sure it’s Synthroid
Find out how Wendy works with her doctor and her pharmacy to make sure she’s getting brand-name Synthroid, as her doctor prescribed.

[H3]

Transcript

Transcript

Making sure it’s Synthroid
ON SCREEN:
WENDY, DIAGNOSED WITH HYPOTHYROIDISM
WENDY:
I had a couple of occasions where I asked for Synthroid, I expected Synthroid, and evidently, that’s not the way it always happens.
At the doctor’s office, we have decided together that he will make notations with my pharmacy, to be Synthroid-specific. It’s nice to know now that I’m going to pick up my prescription and it will be Synthroid. After nearly 15 years, I have put my confidence in Synthroid. It is the right medication for me.
ON SCREEN:
THE FOOD AND DRUG ADMINISTRATION HAS DETERMINED THAT CERTAIN LEVOTHYROXINE PRODUCTS ARE INTERCHANGEABLE.
ON SCREEN:
SYNTHROID IS NOT FOR EVERYONE. TALK TO YOUR DOCTOR TO DETERMINE WHICH MEDICATION IS RIGHT FOR YOU.
WENDY:
My doctor explained to me that it’s very important to take my Synthroid first thing in the morning on an empty stomach and to delay having any caffeine or food for at least 30 minutes. This is not an interruption. I just have one tiny little pill and off I go.
ON SCREEN:
TAKE SYNTHROID AS A SINGLE DOSE, PREFERABLY ON AN EMPTY STOMACH, ONE-HALF TO ONE HOUR BEFORE BREAKFAST.
ON SCREEN:
TO SEE WENDY’S FULL STORY, VISIT THE “SYNTHROID STORIES” SECTION OF SYNTHROID.COM

Hear what other patients are saying

[H2] Myths vs Facts

When your doctor prescribes Synthroid, that might not always be what you'll get at the pharmacy. What do you think, is this a myth or a fact?

Myth
Fact

Sorry, that's incorrect. This is a fact.
1 in 3 people who think they are taking Synthroid aren’t. The FDA has determined that certain levothyroxine products are interchangeable and can be switched at the pharmacy. So if your doctor didn’t note their preference for brand-name Synthroid on the prescription, your pharmacy may switch you to a generic. To ensure you get what your doctor prescribed, check out these tips.
See more myths vs facts

Correct! This is a fact.
1 in 3 people who think they are taking Synthroid aren’t. The FDA has determined that certain levothyroxine products are interchangeable and can be switched at the pharmacy. So if your doctor didn’t note their preference for brand-name Synthroid on the prescription, your pharmacy may switch you to a generic. To ensure you get what your doctor prescribed, check out these tips.
See more myths vs facts

Hide the Answer

[H3] Stay on track with your treatment
Keep this cheat sheet handy for fast facts about Synthroid and how to take it the right way.

Download cheat sheet

[H2] What to expect as you continue taking Synthroid
Hypothyroidism is a lifelong condition that requires lifelong treatment. By continuing to take Synthroid as your doctor prescribed and getting your levels checked regularly, you can help keep your thyroid hormone levels where they should be.

[H3] Real Synthroid stories
Taking the initiative
Elisa talks about how she takes an active role in her hypothyroidism treatment with Synthroid.

[H3]

Transcript

Transcript

Taking the initiative
ELISA:
There is more to managing your hypothyroidism than just taking a pill. It’s not just, you take the pill and that’s it. There’s other facets to this. But it’s manageable and it, it can be done.
ON SCREEN:
TAKING THE INITIATIVE
ELISA:
My role in managing my hypothyroidism is just that. It’s mine.
ON SCREEN:
Elisa
Living with hypothyroidism
ELISA:
And I have to take the responsibility to do that and the initiative to do it. And part of that is making sure that I go to the doctor, my endocrinologist, and being as open as I can be. And when I’m having down days, telling him about it, and when I feel like I’m managing it well or I’m where I need to be within my levels, I also tell him so that everybody’s on the same page.
ON SCREEN:
Your doctor will carefully monitor your thyroid levels regularly.
ELISA:
When I’m feeling off, I definitely

[H1] Synthroid Stories
[H2] Hear from real patients and doctors
From the basics, to diagnosis and treatment, hear from real patients and clinical experts about Synthroid and hypothyroidism.

Diagnosis & treatment
Diagnosis & treatment

Patient stories
Patient stories

[H3] How Synthroid works
Hypothyroidism is a condition that generally requires lifelong treatment. By continuing to take Synthroid as your doctor prescribed and getting your levels checked regularly, you can help keep your thyroid hormone levels where they should be.

[H3]

Transcript

Transcript

How Synthroid works
ON SCREEN:
PART 1: THE THYROID & HYPOTHYROIDISM
NARRATOR:
The thyroid is a small butterfly-shaped gland located at the base of the neck, just below the Adam’s apple. It’s responsible for controlling the body’s metabolism, or the rate at which the body converts food into energy, and for making sure the brain, heart, liver, kidneys, and other organs are working properly.
It does this by creating thyroid hormones that are then circulated through the bloodstream to different parts of the body.
When you have hypothyroidism, the thyroid doesn’t produce, or can’t produce enough thyroid hormones. When your thyroid hormone level decreases, it results in your body’s system slowing down, including your metabolism, which may lead to symptoms such as sensitivity to cold, weight gain, and fatigue.
These are not all the symptoms of hypothyroidism. Your doctor will use a TSH, or thyroid stimulating hormone, test to determine whether you have hypothyroidism.
ON SCREEN:
PART 2: HOW SYNTHROID WORKS
NARRATOR:
Synthroid is a man-made hormone, identical to the hormone made by the thyroid gland and has the same effect on the body. It replaces the amount of hormone the thyroid is unable to or can no longer make, helping to restore your thyroid hormone levels to the range they need to be.
Because your body needs a precise number of thyroid hormone, it’s important to take Synthroid the right way every day, just as your doctor prescribes. This is because how you take Synthroid can affect how well it works.
ON SCREEN:
Tablet shown is not actual size and may not represent exact color.
NARRATOR:
You can learn more about the right way to take Synthroid on this site.
ON SCREEN:
Synthroid.com

[H3] Dr Levy explains hypothyroidism
Hear from clinical expert, Dr Elliot Levy, as they offer an overview of hypothyroidism, its causes, and known risk factors.

[H3]

Transcript

Transcript

Dr. Levy explains hypothyroidism
ON SCREEN:
Physician Talk Videos
ON SCREEN:
Physician Talk
Dr. Elliot Levy, Endocrinologist
ON SCREEN:
AbbVie has compensated Dr. Levy for his appearance. Dr. Levy’s comments and opinions are his own and do not represent those of his associated universities, organizations, or societies.
DR. LEVY:
I did my residency in internal medicine at Washington University in St. Louis, and then I moved to California and I did my post-doctoral fellowship at the University of Southern California in Los Angeles.
ON SCREEN:
What is Hypothyroidism?
DR. LEVY:
Hypothyroidism is a very common condition. Many times you might feel that you’re the only one who has this because you don’t know anybody who suffers from any type of thyroid problems.
ON SCREEN:
Oftentimes it isn’t obvious if a person has hypothyroidism.
DR. LEVY:
Most people who suffer from hypothyroidism are people you would see in the street. Hypothyroidism is caused by a deficiency of thyroid hormone in the blood. In the case of the thyroid gland, the body is producing antibodies to certain elements of the thyroid gland that over a period of time can inflame the thyroid gland, can inhibit the thyroid gland, or in the case of an overactive thyroid can stimulate the thyroid gland.
ON SCREEN:
It tends to run in families and be associated with other autoimmune diseases.
DR. LEVY:
It tends to run in families and it tends to be associated with other autoimmune diseases. So it’s possible that either you or someone in your immediate family may suffer from other autoimmune conditions.

[H3] Managing hypothyroidism: Lisa’s story
Learn why Lisa’s doctor prescribed Synthroid for hypothyroidism, which was a diagnosis she received after she had her thyroid removed.

[H3]

Transcript

Transcript

A SYNTHROID Story: Meet Lisa
ON SCREEN:
Lisa
Living with hypothyroidism
LISA:
Hi, I'm Lisa. I'm a wife and mother of three amazing boys. And I adore my corgi, Mabel.
In my spare time, I love listening to music, I love to restore furniture, and my real passion is writing.
In the fall of 2008, after a routine physical and a series of tests, I was diagnosed with thyroid cancer. That led to meeting with a surgeon, who had to remove my entire thyroid gland. This led to me living with hypothyroidism for the rest of my life.
After my surgery, I met with my endocrinologist, and he taught me all about living with hypothyroidism and that I would have to take, every single day, a thyroid hormone replacement medication. And he prescribed to me, SYNTHROID.
ON SCREEN:
Individual results may vary.
Talk to your doctor to determine which medication is right for you.
LISA:
He told me it would take a while to get the right dosage for me, and that over time, adjustments might need to be made with the amount of SYNTHROID that I would be taking on a daily basis.
ON SCREEN:
Your doctor will carefully monitor your thyroid levels regularly.
Individual results may vary.
LISA:
I've had several different doses over the past almost 16 years. You really have to advocate for yourself, and you have to keep the communication going with your endocrinologist, and be on top of your health, because things happen in life, and sometimes that medicine just needs to be adjusted.
ON SCREEN:
Your doctor will regularly check your TSH blood levels.
LISA:
My doctor told me that I would have to take my medication in the morning, first thing, on an empty stomach, with water, and that I would have to wait about an hour before I had breakfast.
ON SCREEN:
SYNTHROID should be taken alone, with water ONLY, on an empty stomach 30 minutes to 1 hour before breakfast.
LISA:
When I get up in the morning, I take my SYNTHROID first thing, and it's become a routine. I look forward to actually taking that medicine every morning ‘cause that's how I start my day.
Even my dog knows now, like, she'll hear me with the pill bottle. I get up, take my SYNTHROID, and then it's time to go for a walk. So it has to become part of your life, has to become part of your daily routine.
One important thing I have learned over the years is that there are certain foods that can interfere with the absorption of SYNTHROID. So that’s why it’s important to take it only with water.
My doctor also pointed out to me, which I found very interesting, to wait ‘til nighttime to take my calcium supplements and any other vitamins that I do take.
When he writes my prescription, he specifically states SYNTHROID.
ON SCREEN:
The Food and Drug Administration has determined that certain levothyroxine products are interchangeable.
LISA:
I have a terrific relationship with my endocrinologist. Not only because I see him at least four times a year, but it's not just about the treatment. He asks me how I'm doing, how my family is, we just get along really well and he sincerely cares. It’s so important to see that personal side of a physician ‘cause they have it. It's not all clinical and black and white.
They just want to help us. And you have to really nurture that relationship.
If there's one thing I've learned over the past 16 years, it's to listen to my body, because it is telling me when something's just not right and when something needs to be adjusted with my thyroid hormone replacement medication. It's so critical. And it is the answer. It's the key. You have to listen to your body, and you have to communicate with your doctor.
It's been so long that I don't even really think about it anymore. And when my levels are in check and I'm taking my medicine every single day, I feel good. I can move on with life.
LISA:
Knowing that my treatment is consistent gives me confidence.
ON SCREEN:
SYNTHROID is not for everyone.
I need SYNTHROID every day. And thank goodness it's around, because it's going to keep me going, and I'm very fortunate.

[H3] A surprise diagnosis: Wendy’s story
Hear about Wendy's story of receiving a surprise diagnosis of hypothyroidism during her pregnancy and how she took an active role in her treatment.

[H3]

Transcript

Transcript

Handling a surprise diagnosis
ON SCREEN:
WENDY, DIAGNOSED WITH HYPOTHYROIDISM
WENDY:
I just had a very normal visit. The doctor walks in the door and acted very strangely. He said, “Are you tired? Have you been having hair loss or fatigue?” No, I’m golden. What’s the problem? He goes, “Because your thyroid is enlarged, and I can see it from across the room.” He did a thyroid test and he put me on a minimum amount of thyroid medicine. And as the couple of weeks went by, they said, “Well, congratulations you’re pregnant.” So my pregnancy and hypothyroidism happened in my world simultaneously. The pregnancy was probably the bigger bombshell for me because I was facing my 45th birthday. I’d already done the mommy thing and was taking kids off to college. For hypothyroidism, the timing of it was a surprise. But I was already watching for it because my grandmother had it.
ON SCREEN:
TO SEE WENDY’S FULL STORY, VISIT THE “SYNTHROID STORIES” SECTION OF SYNTHROID.COM

[H3] Struggling for a diagnosis: Tracy’s story
Tracy talks about her struggles to get diagnosed with hypothyroidism and finally get treatment with Synthroid.

[H3]

Transcript

Transcript

A Synthroid Story: Meet Tracy
TRACY:
...not taken seriously about your own health is very frustrating, and almost demoralizing, because you know that there’s something wrong, but nobody around you will listen.
ON SCREEN:
TRACY’S STORY
TRACY:
The symptoms that I had when I was — first realized something was wrong, was I was gaining weight, I was having constipation, my hair was falling out. I was really, really tired. And I just felt horrible all the time. And so I went to the doctor, and I told him what my symptoms were and what I was feeling, and he was like, well, um, you’re overweight, you need to eat less, work out more, um, and that’s all that’s wrong. There’s nothing else that could be causing this. And so I went home, confused, because I knew I wasn’t eating a lot. I was very active, as it was, and I needed, I knew there was something more than just that.
ON SCREEN:
Tracy, living with hypothyroidism since 2006
ON SCREEN:
THE JOURNEY TO DIAGNOSIS
TRACY:
So I did some research and I talked to my new healthcare provider. I told him all the symptoms I was having and that I had done some research and I knew something was wrong.
So he said, “let’s check your thyroid out.”
So we ran the TSH test and it came back very high. So we knew that that was the problem.
Being diagnosed with hypothyroidism was kind of a game changer for me. It gave me a reason to know that it wasn’t all in my head, that there was a reason why I had gained weight, and there was a reason why I was so tired all the time and my hair was falling out. And that there was a light at the end of the tunnel and there was something that I could do for it.
ON SCREEN:
DECIDING ON SYNTHROID
TRACY:
After trying a few, uh, medications, my doctor and I decided to try Synthroid because my numbers were not coming down. I was not, um, feeling any better and I was not where I needed to be. And when I started taking it, after taking it for a while, I did start feeling better. So we checked, uh, my TSH level and it was normal.
ON SCREEN:
Your doctor will carefully monitor your thyroid levels regularly Individual results may vary SYNTHROID is not right for everyone
Talk to your doctor to determine which medication is right for you
ON SCREEN:
GETTING WHAT HER DOCTOR PRESCRIBED
TRACY:
My doctor and I decided that Synthroid was what medication that I needed to be on.
The way I make sure that I always get brand name Synthroid at the pharmacy is, first, I look at the bottle to make sure it says “Synthroid” on it; and then I’ll open it up and make sure that the pills that are inside say “Synthroid.”
ON SCREEN:
FINDING RESULTS WITH SYNTHROID
TRACY:
I’ve been on Synthroid for 14 years, and I’m a fan because it works. It is consistent. The dosage is always what is prescribed. And, um, it keeps my TSH where it’s supposed to be.
For me, being on Synthroid means I am taking control of my hypothyroidism.
ON SCREEN:
Take SYNTHROID exactly as your doctor prescribed
Individual results may vary

[H3] Facing hypothyroidism: Elisa’s story
Elisa shares her journey to receive a diagnosis of hypothyroidism and how she learned the proper way to take Synthroid to manage her thyroid hormone levels.

[H3]

Transcript

Transcript

Facing hypothyroidism: Elisa’s story
ELISA:
When I was growing up, I didn’t realize I had a problem. I just knew that there was an issue there. So when I was diagnosed and was reading about each of the symptoms, that’s when I really connected—the symptoms I had in high school and middle school were in fact symptoms and not the normalcy of most day-to-day people.
ON SCREEN:
FACING HYPOTHYROIDISM: ELISA’S STORY
ELISA:
I was technically diagnosed in 2009 by a doctor that I went in just for a physical, and she had felt my neck and pulled back and was like, “Ma’am, your thyroid is swollen.” So although I was diagnosed then,
ON SCREEN:
Elisa
Living with hypothyroidism
ELISA:
and I went and I had just got blood work done, and they called me the next day and told me, I didn’t do anything about it until 2010.
ON SCREEN:
If you are experiencing symptoms, talk to your doctor. Your doctor may decide to have your thyroid levels tested.
ELISA:
Part of the reason that I waited was lack of education. I took anatomy in high school and college, and I knew where the thyroid was, and I knew how to spell it. But beyond that, I knew nothing about its function.
I didn’t really understand that it was going to be a lifelong disease. I didn’t…it was so much to take on, that I had to take time to educate myself before I was willing to go back

[H1] FAQs
[H2] Got questions? We have answers
Find answers to commonly asked questions about hypothyroidism, Synthroid, and support programs here.

[H3] Questions about Synthroid

What is Synthroid used for?

Synthroid is used to restore thyroid hormone levels in people with hypothyroidism (a condition where the thyroid doesn’t produce enough of the thyroid hormone).

What is the difference between Synthroid and a generic version of levothyroxine?

The FDA has determined that certain levothyroxine products are interchangeable and can be switched at the pharmacy. Only Synthroid has the legacy of supporting the hypothyroid community for 70 years.

Questions about dosing

What happens if I miss a dose of Synthroid?

If a dose is missed in the morning, try to take it as soon as possible. If it's been more than a day since your last dose, skip the missed dose and take your normal dose as scheduled. Never take more than your prescribed dose.

How should I store Synthroid?

It’s best to store Synthroid at a room-controlled temperature (68 °F to 77 °F) that’s protected from light and moisture.

Are there foods or supplements that can interfere with the way Synthroid works?​

There are certain foods and supplements that can affect medication absorption.
Foods that may decrease absorption are dietary fiber, walnuts, cottonseed meal, soybean flour, and grapefruit juice.
Supplements that may decrease absorption are iron, calcium, and antacids. Other supplements, such as biotin, may interfere with thyroid test results.
Talk to your doctor about any of these foods or supplements you may be taking.

Questions about payment & the Synthroid Delivers Program

How do I pay for Synthroid? Is Synthroid covered by my insurance?

Synthroid is covered by many commercial insurance programs. There’s also a variety of other methods to help cover the cost of Synthroid including the Synthroid Copay Card and the Synthroid Delivers Program.

How does the Synthroid Delivers Program work?

The Synthroid Delivers Program is a pharmacy service that offers free home delivery of Synthroid.

How can I contact the Synthroid Delivers Program?

Just call at 844-438-7968 to speak with a member of our pharmacy team.
The call center is available Monday-Friday, 8 am-8 pm ET.

Questions about symptoms & side effects

What are the most common side effects when taking Synthroid?

Side effects associated with Synthroid therapy are primarily those of hyperthyroidism due to therapeutic overdosage. General side effects include fatigue, increased appetite, weight loss, heat intolerance, fever, and excessive sweating. With an over-treatment, confusion and disorientation also may occur.
Overtreatment or undertreatment with Synthroid may have negative effects on growth and development, cardiovascular function, bone metabolism, reproductive function, cognitive function, gastrointestinal function, and glucose and lipid metabolism in adult or pediatric patients.
Make sure to talk to your doctor about any side effects you’re experiencing.

How do I know if I have symptoms related to hypothyroidism?

Hypothyroidism must be diagnosed by a doctor through blood tests. Schedule an appointment with your doctor to test for hypothyroidism. Some possible symptoms of hypothyroidism are the following: fatigue, weight gain, trouble tolerating cold, joint and muscle pain, dry skin, dry or thinning hair, heavy or irregular menstrual periods or fertility problems, slowed heart rate, or depression.

If I develop new symptoms, what should I do?

Always keep track of your symptoms even when on Synthroid. Use a journal to record the symptoms you experience and be sure to share them with your doctor.

Can I take magnesium with Synthroid?

Magnesium in certain antacids can affect your body's ability to absorb Synthroid correctly. It's recommended to take Synthroid 4 hours before or after your magnesium supplement.

[H3] Ready to learn more? Start here.
Discover a variety of resources available for download to help you learn more about Synthroid and hypothyroidism.

Explore resources

[H3] Use
SYNTHROID® (levothyroxine sodium) tablets, for oral use is a prescription, man-made thyroid hormone that is used to treat a condition called hypothyroidism in adults and children, including infants. It is meant to replace a hormone that is usually made by your thyroid gland. Generally, thyroid replacement treatment is to be taken for life. SYNTHROID should not be used to treat noncancerous growths or enlargement of the thyroid in patients with normal iodine levels, or in cases of temporary hypothyroidism caused by inflammation of the thyroid gland (thyroiditis).

[H3] Important Safety Information
Thyroid hormones, including SYNTHROID, should not be used either alone or in combination with other drugs for the treatment of obesity or weight loss. In patients with normal thyroid levels, doses of SYNTHROID used daily for hormone replacement are not helpful for weight loss. Larger doses may result in serious or even life-threatening events, especially when used in combination with certain other drugs used to reduce appetite.
Do not use SYNTHROID if you have uncorrected adrenal problems.
Use SYNTHROID only as ordered by your doctor. Taking too much or too little SYNTHROID may lead to negative effects on growth and development, heart function, bone health, reproductive function, mental health, digestive function, and changes in blood sugar and cholesterol metabolism in adult or pediatric patients.
Taking too much levothyroxine may affect your heart, especially if you are elderly or have heart disease. Tell your doctor immediately if you have any signs of increased heart rate, chest pain, or an irregular heartbeat.
Tell your doctor about any other medical conditions you may have, especially heart disease, diabetes, blood clotting problems, and adrenal or pituitary gland problems. The dose of other drugs you may be taking to control these conditions may have to be changed while you are taking SYNTHROID. If you have diabetes, check your blood sugar levels and/or the glucose in your urine, as ordered by your doctor, and immediately tell your doctor if there are any changes. If you are taking blood thinners, your blood clotting status should be checked often.
Taking too much levothyroxine has been associated with increased bone loss, especially in women after menopause.
Tell your doctor if you are pregnant or breastfeeding or are thinking of becoming pregnant while taking SYNTHROID. Your dose of SYNTHROID may need to be increased during your pregnancy.
Tell your doctor if you start experiencing any of the following symptoms: rapid or abnormal heartbeat, chest pain, difficulty catching your breath, leg cramps, headache, nervousness, irritability, sleeplessness, shaking, change in appetite, weight gain or loss, vomiting, diarrhea, increased sweating, difficulty tolerating heat, fever, changes in menstrual periods, swollen red bumps on the skin (hives) or skin rash, or any other unusual medical event.
Partial hair loss may occur during the first few months you are taking SYNTHROID.
Tell your doctor if you are taking any other drugs, including prescription and over-the-counter products.
Products such as iron and calcium supplements and antacids can lower your body’s ability to absorb levothyroxine, so SYNTHROID should be taken 4 hours before or after taking these products.
Tell your doctor or dentist that you are taking SYNTHROID before any surgery.
Use SYNTHROID only as ordered by your doctor. Take SYNTHROID as a single dose, preferably on an empty stomach, one-half to one hour before breakfast.
Once your doctor has found your specific SYNTHROID dose, it is important to have periodic lab tests and clinical evaluations to assess your treatment response.
Foods like soybean flour, cottonseed meal, walnuts, and dietary fiber may cause your body to absorb less SYNTHROID from the gastrointestinal tract. Grapefruit juice may cause your body to absorb less levothyroxine and may reduce its effect. Let your doctor know if you eat these foods, as your dose of SYNTHROID may need to be adjusted.
It may take several weeks before you notice an improvement in your symptoms.
This is the most important safety information you should know about SYNTHROID. For more information, talk with your doctor.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
If you are having difficulty paying for your medicine, AbbVie may be able to help. Visit AbbVie.com/myAbbVieAssist to learn more.
US-SYNT-220158

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Conversely, the presence of this link does not imply the linked site's endorsement of Synthroid.com or AbbVie.
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[H2] Synthroid Copay Full Terms and Conditions
Terms and Conditions apply. This benefit covers SYNTHROID® (levothyroxine sodium). Eligibility: Available only to patients with commercial insurance coverage for SYNTHROID who meet eligibility criteria. The form of co-pay assistance, enrollment requirements, and processes may vary, please call 1-866-627-4980 for additional information. Co-pay assistance program is not available to patients receiving reimbursement under any federal, state, or government-funded insurance programs (for example, Medicare [including Part D], Medicare Advantage, Medigap, Medicaid, TRICARE, Department of Defense, or Veterans Affairs programs) or where prohibited by law or by the patient’s health insurance provider. If you live or receive treatment in certain states, you may not be eligible. If at any time a patient begins receiving drug coverage under any such federal, state, or government-funded healthcare program, patient will no longer be able to use the SYNTHROID Co-pay Savings Card and patient must call 1-866-627-4980 to stop participation. Co-pay assistance provided under this program is offered to and intended for the sole benefit of eligible patients and may not be transferred to or utilized for the benefit of third parties, including, without limitation, third-party insurance plans and/or pharmacy benefit managers and their agents. Patients may not seek reimbursement for value received from the SYNTHROID Co-pay Savings Program from any third-party payers, including insurance plans, flexible spending plans or health savings accounts. Co-pay support made available under this program may not be used with any other coupon, discount, prescription savings card, free trial, or other offer (including any program offered by a third-party insurance plan or pharmacy benefit manager, or an agent of either, that adjusts patient cost-sharing obligations). This is not health insurance. Offer subject to change or discontinuation without notice. Restrictions, including monthly maximums, may apply. Subject to all other terms and conditions, the maximum monthly benefit that may be available solely for the patient’s benefit under the co-pay assistance program is $15.00 per month during the calendar year for patients receiving SYNTHROID every month or $25.00 per month during the calendar year for patients receiving SYNTHROID every 3 months. Patients without health insurance may pay a fixed cash price of $39.95 for a 1-month prescription or $99.90 for a 3-month prescription. The actual application and use of the benefit available under the co-pay assistance program may vary on a monthly, quarterly, and/or annual basis, depending on each individual patient’s plan of insurance and other prescription drug costs. By utilizing this co-pay assistance program, you hereby accept and agree to abide by these terms and conditions. Any individual or entity who enrolls or assists in the enrollment of a patient in the co-pay assistance program represents that the patient meets the eligibility criteria and other requirements described herein. Further, you agree that you currently meet the eligibility criteria and other requirements described herein every time you use the co-pay assistance program. To learn about AbbVie’s privacy practices and your privacy choices, visit https://abbv.ie/corpprivacy.

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Conversely, the presence of this link does not imply the linked site’s endorsement of AbbVie.
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US-SYNT-250279

[H4] Use
SYNTHROID® (levothyroxine sodium) tablets, for oral use is a prescription, man-made thyroid hormone that  is used to treat a condition called hy