Training Example: XEOMIN® (Merz Pharmaceuticals) – Review the Data, Give Your Score & Compare to the Real AI Evaluation

[IMG: XEOMIN® logo for treating frown lines]

[H4] XEOMIN® for:Frown Lines*
*Forehead lines, frown lines and crow's feet. Xeomin is a temporary treatment.

[IMG: XEOMIN® (incobotulinumtoxinA) logo for therapeutic indications]

[H4] XEOMIN® for:Movement Disorders

[IMG: XEOMIN® (incobotulinumtoxinA) logo for therapeutic indications]

[H5] A first–line choice for movement disorders
Patients
[H5] OR
Healthcare Professionals
FIND A DOCTOR
Order Now: 1-855-4MERZTX (1-855-463-7989)

[IMG: XEOMIN® logo for treating frown lines]

[H5] For moderate to severe upper facial lines*
Patients
[H5] OR
Healthcare Professionals
XPERIENCE+™ PROGRAM
FIND A PROVIDER
*Forehead lines, frown lines and crow's feet. Xeomin is a temporary treatment.
Actual Patient. Individual results may vary.

[H6] XEOMIN® (incobotulinumtoxinA) IMPORTANT CONSUMER SAFETY INFORMATION
XEOMIN may cause serious side effects that can be life threatening. Problems swallowing, speaking, or breathing can happen within hours to weeks after an injection of XEOMIN if the muscles that you use to breathe and swallow become weak. Death can happen as a complication if you have severe problems with swallowing or breathing after treatment with XEOMIN.

People with certain breathing problems may need to use muscles in their neck to help them breathe and may be at greater risk for serious breathing problems with XEOMIN.
Swallowing problems may last for several months, and during that time you may need a feeding tube to receive food and water. If swallowing problems are severe, food or liquids may go into your lungs. People who already have swallowing or breathing problems before receiving XEOMIN have the highest risk of getting these problems.

Spread of toxin effects. In some cases, the effect of botulinum toxin may affect areas of the body away from the injection site and cause symptoms of a serious condition called botulism. The symptoms of botulism include: loss of strength and muscle weakness all over the body, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, trouble swallowing.
These symptoms can happen hours to weeks after you receive an injection of XEOMIN. These problems could make it unsafe for you to drive a car or do other dangerous activities.
What is XEOMIN?
XEOMIN is a prescription medicine:
That is injected into muscles and used to improve the look of moderate to severe upper facial lines (frown lines, forehead lines, and crow's feet) in adults for a short period of time (temporary).
that is injected into glands that make saliva and is used to treat long-lasting (chronic) drooling (sialorrhea) in adults and in children 2 years of age and older.
that is injected into muscles and used to:
treat increased muscle stiffness in the arm because of upper limb spasticity in adults.
treat increased muscle stiffness in the arm in children 2 to 17 years of age with upper limb spasticity, excluding spasticity caused by cerebral palsy.
treat the abnormal head position and neck pain with cervical dystonia (CD) in adults.
treat abnormal spasm of the eyelids (blepharospasm) in adults.

It is not known if XEOMIN is safe and effective in children younger than:
2 years of age for the treatment of chronic sialorrhea.
2 years of age for the treatment of upper limb spasticity.
18 years of age for the treatment of glabellar frown lines, cervical dystonia or blepharospasm.
Do not take XEOMIN if you: are allergic to XEOMIN or any of the ingredients in XEOMIN (botulinum toxin type A, human albumin and sucrose), had an allergic reaction to any other botulinum toxin product or have a skin infection at the planned injection site.
Before receiving XEOMIN, tell your doctor about all of your medical conditions, including if you:
have a disease that affects your muscles and nerves (such as amyotrophic lateral sclerosis [ALS or Lou Gehrig's disease], myasthenia gravis or Lambert-Eaton syndrome).
have had any side effect from any other botulinum toxin in the past.
have a breathing problem, such as asthma or emphysema.
have a history of swallowing problems or inhaling food or fluid into your lungs (aspiration).
have bleeding problems.
have drooping eyelids.
have plans to have surgery.
have had eye surgery.
have had surgery on your face.
are pregnant or plan to become pregnant. It is not known if XEOMIN can harm your unborn baby.
are breastfeeding or plan to breastfeed. It is not known if XEOMIN passes into breast milk.
Using XEOMIN with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received XEOMIN in the past. Especially tell your doctor if you:
have received any other botulinum toxin product in the last four months.
have received injections of botulinum toxin in the past. Be sure your doctor knows exactly which product you received. The dose of XEOMIN may be different from other botulinum toxin products that you have received.
have recently received an antibiotic by injection or inhalation.
take muscle relaxants.
take an allergy or cold medicine.
take a sleep medicine.
What should I avoid while taking XEOMIN?
XEOMIN may cause loss of strength or general muscle weakness, blurred vision, or drooping eyelids within hours to weeks of taking XEOMIN. If this happens, do not drive a car, operate machinery, or do other dangerous activities.
What are the possible Side Effects of XEOMIN?
XEOMIN can cause serious side effects including:
Injury to the cornea (the clear front surface of the eye) in people treated for blepharospasm. People who receive XEOMIN to treat spasm of the eyelid may have reduced blinking that can cause a sore on their cornea or other problems of the cornea. Call your healthcare provider or get medical care right away if you have eye pain or irritation after treatment with XEOMIN.
XEOMIN may cause other serious side effects including allergic reactions. Symptoms of an allergic reaction to XEOMIN may include: itching, rash, redness, swelling, wheezing, trouble breathing, or dizziness or feeling faint. Tell your doctor or get medical help right away if you get wheezing or trouble breathing, or if you get dizzy or faint.
The most common side effects of XEOMIN in adults with upper facial lines include:
injection site bruising
The most common side effects of XEOMIN in adults with chronic sialorrhea include:
needing to have a tooth pulled (extracted)
diarrhea
dry mouth
high blood pressure
The most common side effects of XEOMIN in children 2 to 17 years of age with chronic sialorrhea include:
bronchitis
headache
nausea
vomiting
The most common side effects of XEOMIN in adults with upper limb spasticity include:
seizure
dry mouth
nasal congestion, sore throat and runny nose
upper respiratory infection
The most common side effects of XEOMIN in children 2 to 17 years of age with upper limb spasticity include:
nasal congestion, sore throat and runny nose
bronchitis
The most common side effects of XEOMIN in adults with cervical dystonia include:
difficulty swallowing
pain at the injection site
neck pain
muscle and bone pain
muscle weakness
The most common side effects of XEOMIN in adults with blepharospasm include:
drooping of the eyelid
vision problems
dry eye
dry mouth
These are not all the possible side effects of XEOMIN.
Call your doctor for medical advice about side effects.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Please see Full Prescribing Information and Medication Guide.

[H4]
XEOMIN offers patients A DURABLE NEUROTOXIN AS RESILIENT AS THEY ARE

Designed with Purity in mind, XEOMIN contains only the active neurotoxin
Over time, repeated exposure to therapeutic proteins can contribute to a decrease in treatment response. XEOMIN is developed using proprietary XTRACT Technology® manufacturing process that removes the complexing proteins.

[H4]
What can waning efficacy look or sound like?

[H6]
Decreased Satisfaction1
Patients say the drug doesn't work as well as it used to

[H6]
Increased Dosing1
Patients appear to require an increased dose in order to maintain efficacy or regain lost efficacy

[H6]
Higher Frequency1
Patients are requesting shorter dosing intervals because they are experiencing decreased response

[H6]
Loss of Patients
Patients feel less motivated to come back for reinjection or are lost to
follow-up

See how XEOMIN keeps patients in their fight

Administering XEOMIN
[H2] Reconstitution to Flip For
Prepare XEOMIN for injection in 3 straightforward steps.
Learn to
Reconstitute XEOMIN

[IMG: A bottle of XEOMIN; indicated for pediatric chronic sialorrhea, upper limb spasticity, cervical dystonia, and blepharospasm]

Merz has your back
[H2] Reimbursement
Offering comprehensive support services for your patients.
Get Support with Merz Connect

[H5]
XEOMIN is broadly covered
for FDA-approved indications with Top National Payers
Learn More

[IMG: A man, woman, and child that are excellent candidates for XEOMIN]

[H2] Stay in Fighting Shape

Request a Rep

*First line indicates no step therapy is required for XEOMIN patients if they meet clinical eligibility requirements as defined by each payer policy.

References
Carr WW, Jain N, Sublett JW. Immunogenicity of botulinum toxin formulations: potential therapeutic implications. Adv Ther. 2021;38(10):5046-5064.

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[H6] IMPORTANT SAFETY INFORMATION INCLUDING BOXED WARNING

[H6] WARNING: DISTANT SPREAD OF TOXIN EFFECT
See full prescribing information for complete BOXED WARNING.
The effects of XEOMIN and all botulinum toxin products may spread from the area of injection to produce symptoms
consistent with botulinum toxin effects. These symptoms have been reported hours to weeks after injection. Swallowing
and breathing difficulties can be life threatening and there have been reports of death. The risk of symptoms is probably
greatest in children treated for spasticity but symptoms can also occur in adults, particularly in those patients who have
underlying conditions that would predispose them to these symptoms.

[H6] INDICATIONS
XEOMIN® (incobotulinumtoxinA) for injection is indicated for the treatment of:
Chronic sialorrhea in patients 2 years of age and older
Upper limb spasticity in adults
Upper limb spasticity in pediatric patients 2 to 17 years of age, excluding spasticity caused by cerebral palsy
Cervical dystonia in adults
Blepharospasm in adults

[H6] IMPORTANT SAFETY INFORMATION (continued)

[H6] CONTRAINDICATIONS

Known hypersensitivity to any botulinum toxin product or to any of the components (human albumin, sucrose) in the formulation.
Infection at the proposed injection site(s) because it could lead to severe local or disseminated infection.

[H6] WARNINGS AND PRECAUTIONS

The potency units of XEOMIN are specific to the preparation and assay method utilized. Units of biological activity of Xeomin cannot be compared to or converted into Units of any other botulinum toxin products assessed with any other specific assay method.
Serious hypersensitivity reactions (anaphylaxis, serum sickness, urticaria, soft tissue edema, and dyspnea) have been reported with botulinum toxin products. If serious and/or immediate hypersensitivity reactions occur, discontinue further injection of XEOMIN and institute appropriate medical therapy immediately.
Treatment with XEOMIN and other botulinum toxin products can result in swallowing or breathing difficulties. Patients with pre-existing swallowing or breathing difficulties may be more susceptible to these complications. When distant effects occur, additional respiratory muscles may be involved. Patients may require immediate medical attention should they develop problems with swallowing, speech, or respiratory disorders. Dysphagia may persist for several months, which may require use of a feeding tube. Aspiration may result from severe dysphagia.
Individuals with peripheral motor neuropathic diseases, amyotrophic lateral sclerosis, or neuromuscular junctional disorders (e.g., myasthenia gravis or Lambert-Eaton syndrome) may be at increased risk for severe dysphagia and respiratory compromise from typical doses of XEOMIN.
Cervical Dystonia: Treatment with botulinum toxins may weaken neck muscles that serve as accessory muscles of ventilation. This may result in critical loss of breathing capacity in patients with respiratory disorders who may have become dependent upon these accessory muscles. There have been post- marketing reports of serious breathing difficulties, including respiratory failure, in patients with cervical dystonia treated with botulinum toxin products. Patients with smaller neck muscle mass and patients who require bilateral injections into the sternocleidomastoid muscles are at greater risk of dysphagia. Limiting the dose injected into the sternocleidomastoid muscle may decrease the occurrence of dysphagia.
Blepharospasm: Reduced blinking from injection of botulinum toxin products into the orbicularis muscle can lead to corneal exposure, persistent epithelial defect, and corneal ulceration, especially in patients with VII nerve disorders. Patients with previous eye surgery should be carefully assessed for corneal sensation before treatment. Xeomin should be used with caution in patients at risk of developing narrow angle glaucoma. To decrease the risk for ectropion, XEOMIN should not be injected into the medial lower eyelid area.
XEOMIN contains human serum albumin. Based on effective donor screening and product manufacturing processes, it carries an extremely remote risk for transmission of viral diseases and variant Creutzfeldt-Jakob disease (vCJD). There is a theoretical risk for transmission of Creutzfeldt-Jakob disease (CJD). No cases of transmission of viral diseases, CJD, or vCJD have ever been reported for licensed albumin or albumin contained in other licensed products.
Use caution when XEOMIN is used where the targeted muscle shows excessive weakness or atrophy.
Use caution when XEOMIN is used in patients who have marked facial asymmetry, with surgical alterations to the facial anatomy, pre-existing eyelid or eyebrow ptosis, when excessive weakness or atrophy is present in the target muscles, excessive dermatochalasis, deep dermal scarring, thick sebaceous skin (e.g., the inability to substantially lessen glabellar lines even by physically spreading them apart).

[H6] ADVERSE REACTIONS
The most commonly observed adverse reactions at rates specified below and greater than placebo are:
Chronic Sialorrhea:
in adults (≥4% of patients): tooth extraction, dry mouth, diarrhea, and hypertension.
in pediatric patients (≥1% of patients): bronchitis, headache, and nausea/vomiting.

Upper Limb Spasticity
in adults (≥2% of patients): seizure, nasopharyngitis, dry mouth, and upper respiratory tract infection.
in pediatric patients (≥3% of patients): nasopharyngitis and bronchitis.

Cervical Dystonia in adults (≥5% of patients): dysphagia, neck pain, muscle weakness, injection site pain, and musculoskeletal pain.
Blepharospasm in adults (≥10% of patients): eyelid ptosis, dry eye, visual impairment, and dry mouth.

[H6] DRUG INTERACTIONS
Co-administration of XEOMIN and aminoglycoside or other agents interfering with neuromuscular transmission, (e.g., muscle relaxants), should only be performed with caution as these agents may potentiate the effect of the toxin.
Use of anticholinergic drugs after administration of XEOMIN may potentiate systemic anticholinergic effects.
The effect of administering different botulinum toxin products at the same time or within several months of each other is unknown. Excessive neuromuscular weakness may be exacerbated by administration of another botulinum toxin prior to the resolution of the effects of a previously administered botulinum toxin.
Excessive weakness may also be exaggerated by administration of a muscle relaxant before or after administration of XEOMIN.
[H6] USE IN PREGNANCY
XEOMIN should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
[H6] PEDIATRIC USE
Safety and effectiveness of XEOMIN have not been established in pediatric patients for lower limb spasticity, cervical dystonia, or blepharospasm.
Safety and effectiveness have been established in pediatric patients 2 to 17 years of age in patients with chronic sialorrhea and upper limb spasticity. A pediatric assessment for XEOMIN in upper limb spasticity demonstrates that XEOMIN is safe and effective in another pediatric population. However, XEOMIN is not approved for such patient population due to marketing exclusivity for another botulinum toxin.
Visit www.xeomin.com to obtain the Full Prescribing Information and Medication Guide.

View More

[H6] IMPORTANT SAFETY INFORMATION INCLUDING BOXED WARNING

[H6] WARNING: DISTANT SPREAD OF TOXIN EFFECT
See full prescribing information for complete BOXED WARNING.
The effects of XEOMIN and all botulinum toxin products may spread from the area of injection to produce symptoms
consistent with botulinum toxin effects. These symptoms have been reported hours to weeks after injection. Swallowing
and breathing difficulties can be life threatening and there have been reports of death. The risk of symptoms is probably
greatest in children treated for spasticity but symptoms can also occur in adults, particularly in those patients who have
underlying conditions that would predispose them to these symptoms.

[H6] INDICATIONS
XEOMIN® (incobotulinumtoxinA) for injection is indicated for the treatment of:
Chronic sialorrhea in patients 2 years of age and older
Upper limb spasticity in adults
Upper limb spasticity in pediatric patients 2 to 17 years of age, excluding spasticity caused by cerebral palsy
Cervical dystonia in adults
Blepharospasm in adults

[H6] IMPORTANT SAFETY INFORMATION (continued)

[H6] CONTRAINDICATIONS

Known hypersensitivity to any botulinum toxin product or to any of the components (human albumin, sucrose) in the formulation.
Infection at the proposed injection site(s) because it could lead to severe local or disseminated infection.

[H6] WARNINGS AND PRECAUTIONS

The potency units of XEOMIN are specific to the preparation and assay method utilized. Units of biological activity of Xeomin cannot be compared to or converted into Units of any other botulinum toxin products assessed with any other specific assay method.
Serious hypersensitivity reactions (anaphylaxis, serum sickness, urticaria, soft tissue edema, and dyspnea) have been reported with botulinum toxin products. If serious and/or immediate hypersensitivity reactions occur, discontinue further injection of XEOMIN and institute appropriate medical therapy immediately.
Treatment with XEOMIN and other botulinum toxin products can result in swallowing or breathing difficulties. Patients with pre-existing swallowing or breathing difficulties may be more susceptible to these complications. When distant effects occur, additional respiratory muscles may be involved. Patients may require immediate medical attention should they develop problems with swallowing, speech, or respiratory disorders. Dysphagia may persist for several months, which may require use of a feeding tube. Aspiration may result from severe dysphagia.
Individuals with peripheral motor neuropathic diseases, amyotrophic lateral sclerosis, or neuromuscular junctional disorders (e.g., myasthenia gravis or Lambert-Eaton syndrome) may be at increased risk for severe dysphagia and respiratory compromise from typical doses of XEOMIN.
Cervical Dystonia: Treatment with botulinum toxins may weaken neck muscles that serve as accessory muscles of ventilation. This may result in critical loss of breathing capacity in patients with respiratory disorders who may have become dependent upon these accessory muscles. There have been post- marketing reports of serious breathing difficulties, including respiratory failure, in patients with cervical dystonia treated with botulinum toxin products. Patients with smaller neck muscle mass and patients who require bilateral injections into the sternocleidomastoid muscles are at greater risk of dysphagia. Limiting the dose injected into the sternocleidomastoid muscle may decrease the occurrence of dysphagia.
Blepharospasm: Reduced blinking from injection of botulinum toxin products into the orbicularis muscle can lead to corneal exposure, persistent epithelial defect, and corneal ulceration, especially in patients with VII nerve disorders. Patients with previous eye surgery should be carefully assessed for corneal sensation before treatment. Xeomin should be used with caution in patients at risk of developing narrow angle glaucoma. To decrease the risk for ectropion, XEOMIN should not be injected into the medial lower eyelid area.
XEOMIN contains human serum albumin. Based on effective donor screening and product manufacturing processes, it carries an extremely remote risk for transmission of viral diseases and variant Creutzfeldt-Jakob disease (vCJD). There is a theoretical risk for transmission of Creutzfeldt-Jakob disease (CJD). No cases of transmission of viral diseases, CJD, or vCJD have ever been reported for licensed albumin or albumin contained in other licensed products.
Use caution when XEOMIN is used where the targeted muscle shows excessive weakness or atrophy.
Use caution when XEOMIN is used in patients who have marked facial asymmetry, with surgical alterations to the facial anatomy, pre-existing eyelid or eyebrow ptosis, when excessive weakness or atrophy is present in the target muscles, excessive dermatochalasis, deep dermal scarring, thick sebaceous skin (e.g., the inability to substantially lessen glabellar lines even by physically spreading them apart).

[H6] ADVERSE REACTIONS
The most commonly observed adverse reactions at rates specified below and greater than placebo are:
Chronic Sialorrhea:
in adults (≥4% of patients): tooth extraction, dry mouth, diarrhea, and hypertension.
in pediatric patients (≥1% of patients): bronchitis, headache, and nausea/vomiting.

Upper Limb Spasticity
in adults (≥2% of patients): seizure, nasopharyngitis, dry mouth, and upper respiratory tract infection.
in pediatric patients (≥3% of patients): nasopharyngitis and bronchitis.

Cervical Dystoni

[H6] XEOMIN® (incobotulinumtoxinA) IMPORTANT CONSUMER SAFETY INFORMATION
XEOMIN may cause serious side effects that can be life threatening. Problems swallowing, speaking, or breathing can happen within hours to weeks after an injection of XEOMIN if the muscles that you use to breathe and swallow become weak. Death can happen as a complication if you have severe problems with swallowing or breathing after treatment with XEOMIN.

People with certain breathing problems may need to use muscles in their neck to help them breathe and may be at greater risk for serious breathing problems with XEOMIN.
Swallowing problems may last for several months, and during that time you may need a feeding tube to receive food and water. If swallowing problems are severe, food or liquids may go into your lungs. People who already have swallowing or breathing problems before receiving XEOMIN have the highest risk of getting these problems.

Spread of toxin effects. In some cases, the effect of botulinum toxin may affect areas of the body away from the injection site and cause symptoms of a serious condition called botulism. The symptoms of botulism include: loss of strength and muscle weakness all over the body, double vision, blurred vision and drooping eyelids, hoarseness or change or loss of voice, trouble saying words clearly, loss of bladder control, trouble breathing, trouble swallowing.
These symptoms can happen hours to weeks after you receive an injection of XEOMIN. These problems could make it unsafe for you to drive a car or do other dangerous activities.
What is XEOMIN?
XEOMIN is a prescription medicine:
That is injected into muscles and used to improve the look of moderate to severe upper facial lines (frown lines, forehead lines, and crow's feet) in adults for a short period of time (temporary).
that is injected into glands that make saliva and is used to treat long-lasting (chronic) drooling (sialorrhea) in adults and in children 2 years of age and older.
that is injected into muscles and used to:
treat increased muscle stiffness in the arm because of upper limb spasticity in adults.
treat increased muscle stiffness in the arm in children 2 to 17 years of age with upper limb spasticity, excluding spasticity caused by cerebral palsy.
treat the abnormal head position and neck pain with cervical dystonia (CD) in adults.
treat abnormal spasm of the eyelids (blepharospasm) in adults.

It is not known if XEOMIN is safe and effective in children younger than:
2 years of age for the treatment of chronic sialorrhea.
2 years of age for the treatment of upper limb spasticity.
18 years of age for the treatment of glabellar frown lines, cervical dystonia or blepharospasm.
Do not take XEOMIN if you: are allergic to XEOMIN or any of the ingredients in XEOMIN (botulinum toxin type A, human albumin and sucrose), had an allergic reaction to any other botulinum toxin product or have a skin infection at the planned injection site.
Before receiving XEOMIN, tell your doctor about all of your medical conditions, including if you:
have a disease that affects your muscles and nerves (such as amyotrophic lateral sclerosis [ALS or Lou Gehrig's disease], myasthenia gravis or Lambert-Eaton syndrome).
have had any side effect from any other botulinum toxin in the past.
have a breathing problem, such as asthma or emphysema.
have a history of swallowing problems or inhaling food or fluid into your lungs (aspiration).
have bleeding problems.
have drooping eyelids.
have plans to have surgery.
have had eye surgery.
have had surgery on your face.
are pregnant or plan to become pregnant. It is not known if XEOMIN can harm your unborn baby.
are breastfeeding or plan to breastfeed. It is not known if XEOMIN passes into breast milk.
Using XEOMIN with certain other medicines may cause serious side effects. Do not start any new medicines until you have told your doctor that you have received XEOMIN in the past. Especially tell your doctor if you:
have received any other botulinum toxin product in the last four months.
have received injections of botulinum toxin in the past. Be sure your doctor knows exactly which product you received. The dose of XEOMIN may be different from other botulinum toxin products that you have received.
have recently received an antibiotic by injection or inhalation.
take muscle relaxants.
take an allergy or cold medicine.
take a sleep medicine.
What should I avoid while taking XEOMIN?
XEOMIN may cause loss of strength or general muscle weakness, blurred vision, or drooping eyelids within hours to weeks of taking XEOMIN. If this happens, do not drive a car, operate machinery, or do other dangerous activities.
What are the possible Side Effects of XEOMIN?
XEOMIN can cause serious side effects including:
Injury to the cornea (the clear front surface of the eye) in people treated for blepharospasm. People who receive XEOMIN to treat spasm of the eyelid may have reduced blinking that can cause a sore on their cornea or other problems of the cornea. Call your healthcare provider or get medical care right away if you have eye pain or irritation after treatment with XEOMIN.
XEOMIN may cause other serious side effects including allergic reactions. Symptoms of an allergic reaction to XEOMIN may include: itching, rash, redness, swelling, wheezing, trouble breathing, or dizziness or feeling faint. Tell your doctor or get medical help right away if you get wheezing or trouble breathing, or if you get dizzy or faint.
The most common side effects of XEOMIN in adults with upper facial lines include:
injection site bruising
The most common side effects of XEOMIN in adults with chronic sialorrhea include:
needing to have a tooth pulled (extracted)
diarrhea
dry mouth
high blood pressure
The most common side effects of XEOMIN in children 2 to 17 years of age with chronic sialorrhea include:
bronchitis
headache
nausea
vomiting
The most common side effects of XEOMIN in adults with upper limb spasticity include:
seizure
dry mouth
nasal congestion, sore throat and runny nose
upper respiratory infection
The most common side effects of XEOMIN in children 2 to 17 years of age with upper limb spasticity include:
nasal congestion, sore throat and runny nose
bronchitis
The most common side effects of XEOMIN in adults with cervical dystonia include:
difficulty swallowing
pain at the injection site
neck pain
muscle and bone pain
muscle weakness
The most common side effects of XEOMIN in adults with blepharospasm include:
drooping of the eyelid
vision problems
dry eye
dry mouth
These are not all the possible side effects of XEOMIN.
Call your doctor for medical advice about side effects.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.
Please see Full Prescribing Information and Medication Guide.