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[H2] DIFFERIN 0.1% ADAPALENE GEL TREATMENT

Differin® Gel contains the retinoid adapalene, the first over-the-counter active ingredient for acne in more than 30 years. It's what you and your skin have been waiting for to treat acne for consistently clearer skin.

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[H2] "How to use Differin Adapalene Gel Retinoid It's time to rethink how you apply your acne treatment for effective results."

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[H1] Differin 0.1% Adapalene Gel Treatment

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[H2] Differin 0.1% Adapalene Gel Treatment

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Take a different approach to clearing—and preventing—your acne with Differin Adapalene Gel Retinoid Treatment. When used every single day, Differin Gel can reduce up to 87% of acne in up to 12 weeks *based on an in-vitro laboratory study.

Treats acne with the power of Rx, without a prescription needed
Prevents breakouts, blackheads, whiteheads, blemishes and clogged pores by regulating skin cell turnover
Restores skin tone and texture by clearing acne
Acts as an anti-inflammatory agent to reduce acne and redness
Available in 15g (up to 30-day supply) and 45g (up to 90-day supply)
Find it in a tube or easy-to-use pump
Differin® Gel can be used to effectively treat acne or “maskne” caused by wearing face masks or facial coverings

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[H2] HOW TO USE

How to use Differin Adapalene Gel Retinoid

It’s time to rethink how you apply your acne treatment for consistently clearer skin

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[H2] FEATURES

Non-comedogenic, fragrance-free Differin® Gel contains the retinoid adapalene, the first over-the-counter active ingredient for acne created by Differin. It’s what you and your skin have been waiting for consistently clearer skin.

[H2] THE ROUTINE

[IMG: gentle cleanser]

STEP 1: CLEANSE

Daily Oil-Free Hydrating Cleanser

This hydrating cleanser features a unique amino-acid based cleansing system that dissolves surface oil and impurities

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[H2]

Daily Oil-Free Hydrating Cleanser
Daily Oil-Free Hydrating Cleanser

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[IMG: gentle cleanser]

STEP 2: TREAT

Differin 0.1% Adapalene Gel Treatment

Next apply a pea-sized amount of Differin® Gel retinoid once every day all over your face even when your face is clear for long-term results.

[IMG: Differin 0.1% Adapalene Gel Treatment]

[H2]

Differin 0.1% Adapalene Gel Treatment
Differin 0.1% Adapalene Gel Treatment

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Step 3: MOISTURIZE

Oil Absorbing Moisturizer with sunscreen is an integral step to your daily skincare routine​.Apply liberally 15 minutes before sun exposure and reapply at least every two hours.

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[H2]

Oil Absorbing Moisturizer SPF 30
Oil Absorbing Moisturizer SPF 30

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[H2] ALL INGREDIENTS

[H2] ACTIVE INGREDIENTS

Adapalene 0.1% (retinoid)

[H2] INACTIVE INGREDIENTS

Carbomer 940,Edetate Disodium, Methylparaben, Poloxamer 182, Propylene Glycol, Purified water and Sodium Hydroxide .may contain Hydrochloric Acid to adjust pH.

[H2] FAQ

[H3] What does Differin® Gel do to clear acne?

Differin® Gel contains adapalene, a type of retinoid. Topical retinoids, like Differin® Gel, play a crucial role in the treatment of acne. Retinoids have vitamin A activity which helps regulate cell turnover to make sure your skin goes through the right process, creating a healthier environment for skin. Regulating cell turnover helps to keep the pores from clogging and target acne before it even starts. Don’t think of Differin® Gel as a spot treatment only to be used when acne rears its ugly head. In fact, if used daily,
Differin® Gel stops new acne from forming, resulting in improved skin tone and texture.

[H3] What is Differin® Gel?

Differin contains the only full prescription fighting retinoid available over the counter: adapalene. It’s the first new OTC active ingredient to treat acne approved by the FDA in more than 30 years.

[H3] How long has Differin® Gel been on the market?

Differin® Gel is dermatologist-developed, and its active ingredient — adapalene — has been prescribed to over 40 million people globally for more than 20 years. It was approved by the FDA for over-the-counter use without a prescription in 2016.

[H3] What makes Differin® Gel unique from other options currently available?

Differin® Gel contains adapalene, a multi-benefit, dermatologist-recommended retinoid, available without a prescription, to clear breakouts where they start (deep in the pores); prevent acne before it begins; and, as a result, restore the skin’s texture and tone.

[H3] Is Differin® Gel dermatologist developed and tested?

Yes, Differin® Gel is dermatologist developed and includes a dermatologist-recommended retinoid.
According to the American Academy of Dermatology’s (AAD) therapeutic treatment guidelines, topical retinoids like adapalene are recommended as a primary therapy for initial treatment of mild and moderate acne, even ahead of popular over-the-counter products that contain salicylic acid. The AAD is the largest organization of dermatologists (over 19,000 worldwide) who provide public education about dermatology and dermatologic health.

[H2]
Reviews

Rated 5 out of
5
by
BCCS from
Keeps my hormonal acne at bay!
I have struggled with hormonal acne for YEARS and after a really bad breakout, I decided I would try this because I felt I had tried everything else. So I started using a gentle cleanser and moisturizer, and differin gel every night. My sensitive skin did not have any negative reactions, besides getting a little worse before it got better. But after a few months, my skin had never looked better. I have oily, sensitive skin for reference and had been getting cystic, nodule acne for EVER before using this product. Now I get acne every now and then but nothing like it was before. Thank you, thank you, thank you!
Date published: 2022-09-12

Rated 5 out of
5
by
jillian5 from
Differin Gel
I was so excited to try this, as I have used the prescription Differin gel in the past and it worked well for me. This is such an easy and affordable option for me to be able to simply pick it up while I'm out shopping anyway! I haven't noticed any skin irritation or dryness, and I have had a significant improvement in my acne - I even had someone compliment me on how clear my skin is this week! That's never happened! Overall, I'd recommend this product to anyone who is looking for a prescription quality product without having to make a trip to the doctor! I received a sample of this product in order to facilitate my review, but all opinions are my own.
Date published: 2017-04-04

Rated 5 out of
5
by
AlyM from
Great product!
I have pretty clear skin in general but my chin tends to break out from hormonal fluctuations and those acne spots are deep and can stick around for a month or more. They typically leave skin discoloration behind that takes up to a year to fade. I've been using the Differin Gel only on my chin for the last few months and I've only had one chin breakout and it lasted for a shorter period of time. I haven't experienced any skin sensitivity to the retinoid and have been using it every night. I received this product for free in return for an honest review. I will purchase the product once my sample runs out and I'd definitely recommend this product to others.
Date published: 2017-10-26

Rated 5 out of
5
by
Estelle from
A REAL solution to my hormonal Acne!!!!
I’ve been using differin gel for two weeks now and my skin already looks SO much better. I’ve struggled with hormonal acne since the age of 13 and I’ve tried everything on the market. If you are like me and are looking for a solution I highly recommend using differin gel. This product is also reducing my post acne marks and scars. My skin is obviously not perfect, however that is the beauty of this product, the longer you use it, the better the results will be! This product did not irritate my sensitive skin, however I did experience a mild purging period which is normal. After the first week my skin was already less inflamed and starting to look different. GO GET THIS!!!!
Date published: 2020-09-06

Rated 1 out of
5
by
EJC8 from
Painful.
Differin was something new I wanted to try because I was experiencing minor flare ups more frequently than I had in the past. So I tried it and within a few days my face was red, flakey, and bruised. I had red rims around my eyes that looked purple and were peeling so badly. I researched which moisturizers to use with the gel and used those as well as followed every direction. That being said I had no success with this product, as every time I would put it on it would burn so badly I felt like screaming. I will no longer be using this product and I hope that my skin will be able to recover from this as I have seen reviews that say they haven’t.
Date published: 2022-04-10

Rated 5 out of
5
by
Jilly from
AMAZING!!!!!
The past four months have been terrible. I suffered from horrible, painful cystic acne all over my chin and jawline. As a 37 year old business woman this was horrifying and embarrassing beyond belief. I saw an ad for Differin in a magazine and I ran out to Walgreens same day to pick up a tube. It's now day 16 and already all my cysts are gone, I have a few tiny pimples left and the red scars but my skin is soft and clearing so nicely. It's shocking how fast it happened. I had lost my confidence and was in tears daily, today I feel self confident again and can look in the mirror without feeling sick. I would add pictures but I didn't take any out of embarrassment. Thank you so much Differin!!! I will use this for years to come.
Date published: 2017-08-21

Rated 5 out of
5
by
Laura from
Freaking miracle!
So I did not have ANY acne as a teen I actually had great skin. Now that I am 24 and I have been vegan for 3 years I developed adult hormonal cystic ance and for the most part it is on my chin and cheeks. I was having awful breakouts on my forehead but I fixed that with probiotics. It took about 3 months for my face to fully clear up but It was so bad before. This was my last resort and I am so glad I tried it. One thing I will say is to get a good natural moisturizer with spf for the day time and a really rich one for night time. I used andalou naturals and naked co for moisturizers.
Date published: 2017-05-04

Rated 5 out of
5
by
LeslieE82 from
The Best!
I received a full size product of Differin gel from Poshly complimentary for testing purposes. This is THEE best acne gel I've ever tried! I used the product over the course of 12 weeks, every day at night. At first it seemed to draw more oil out of my skin and create more acne. But, after the first couple of weeks the acne started to subside and clear up. Over time I've noticed less acne to form and the texture of my skin has improved. A little really does go a long way and the best attribute of all is that it never stung, never left a residue and never dried my skin out. I definitely plan to purchase another tube when this runs out.
Date published: 2017-11-17

Differin Gel Reviews - page 2
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[H2]
Questions

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[IMG: DIFFERIN EPIDUO ACNE GEL]

[H2]

DIFFERIN EPIDUO ACNE GEL
DIFFERIN EPIDUO ACNE GEL

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[IMG: Differin 0.1% Adapalene Gel Treatment]

[H2]

Differin 0.1% Adapalene Gel Treatment
Differin 0.1% Adapalene Gel Treatment

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Power Patch Fast Fix
Power Patch Fast Fix

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5% Benzoyl Peroxide Daily Deep Cleanser
5% Benzoyl Peroxide Daily Deep Cleanser

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[H2]

Dark Spot Correcting Serum
Dark Spot Correcting Serum

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10% Benzoyl Peroxide Maximum Strength Acne Foaming Cleanser
10% Benzoyl Peroxide Maximum Strength Acne Foaming Cleanser

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[H2]

Power Patch Skin Restore
Power Patch Skin Restore

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[H1] FAQ

[H2] FAQ about Differin® Gel

1

[H3]
What is Differin® Gel?

Differin contains the only full prescription fighting retinoid available over the counter: adapalene. It’s the first new OTC active ingredient to treat acne approved by the FDA in more than 30 years.

2

[H3]
How long has Differin® Gel been on the market?

Differin® Gel is dermatologist-developed, and its active ingredient — adapalene — has been prescribed to over 40 million people globally for more than 20 years. It was approved by the FDA for over-the-counter use without a prescription in 2016.

3

[H3]
What makes Differin® Gel unique from other options currently available?

Differin® Gel contains adapalene, a multi-benefit, dermatologist-recommended retinoid, available without a prescription, to clear breakouts where they start (deep in the pores); prevent acne before it begins; and, as a result, restore the skin’s texture and tone.

4

[H3]
Is Differin® Gel dermatologist developed and tested?

Yes, Differin® Gel is dermatologist developed and includes a dermatologist-recommended retinoid. According to the American Academy of Dermatology’s (AAD) therapeutic treatment guidelines, topical retinoids like adapalene are recommended as a primary therapy for initial treatment of mild and moderate acne, even ahead of popular over-the-counter products that contain salicylic acid. The AAD is the largest organization of dermatologists (over 19,000 worldwide) who provide public education about dermatology and dermatologic health.

5

[H3]
Is Differin® Gel FDA approved?

Yes, Differin® Gel (adapalene 0.1%) is FDA-approved for over-the-counter treatment of acne (acne vulgaris). For more than 20 years, doctors have prescribed the retinoid found in Differin® Gel to over 40 million people globally.

6

[H3]
Is there still a prescription version of Differin® Gel?

Differin® Gel (adapalene 0.1%) was launched in stores and online, available without a prescription, in January 2017. Other products containing adapalene are still available with a prescription.

[H3] FAQ about retinoids and adapalene

1

[H3]
What are retinoids, and why are they important in clearing acne?

Topical retinoids, like Differin® Gel, play a crucial role in the treatment of acne. In 1925, studies linked abnormal cell turnover to vitamin A deficiencies. Retinoids have vitamin A activity and help regulate that turnover to make sure your skin goes through the right process, creating a healthier environment for skin. Regulating skin cell turnover to a normal rate helps to keep the pores from clogging and target acne before it even starts. Through the years, researchers developed different forms of retinoids, which have become the basis for many prescription acne medications.

2

[H3]
Are all retinoids the same?

No, not all retinoids are created equal. There are currently three retinoids in use for topical acne medications — adapalene (over the counter and prescription), tretinoin and tazarotene. Differin® Gel uses adapalene, an ingredient designed with improved tolerability in mind, resulting in less redness and skin irritation. Adapalene has shown in studies to have superior tolerability compared to other prescription retinoid products not containing adapalene. Adapalene is also the first multi-benefit retinoid acne ingredient available over the counter, without a prescription. Benefits include:Continually renews skin cells to help prevent pores from cloggingActing as an anti-inflammatory agent to reduce redness and swelling at the sourceRestoring skin tone and texture by clearing acne

3

[H3]
What is the difference between retinoid and retinol?

Retinol is a type of retinoid found in many cosmetic products. However, adapalene is much more powerful than retinol, and it’s the only FDA-approved retinoid available for OTC use to clear acne.

4

[H3]
What is the percentage of retinoid ingredient found in Differin® Gel?

Differin® Gel is the only OTC acne treatment to contain a prescription-strength retinoid. This powerful medication contains 0.1% adapalene to clear acne.

[H2] FAQ about the Differin difference

1

[H3]
I’ve heard salicylic acid and benzoyl peroxide are also effective treatments for acne. How are retinoids different?

Adapalene is the newest advancement in acne treatment available without a prescription in over 30 years; it’s able to effectively target two causes of acne. Differin® Gel clears redness and inflammation associated with acne and helps prevent pimples, blackheads and clogged pores before they occur.
[H2] Adapalene vs. other over-the-counter acne treatments

Active Ingredients:
Adapalene
Benzoyl Peroxide
Salicylic Acid

Clears acne, prevents acne to restore skin texture and tone
YES
YES
YES

Balances skin cell production to treat acne
YES
NO
NO

Significant anti-inflammatory benefit
YES
NO
NO

Once-a-day application provides 24-hour action
YES
NO
NO

Safe for clothing and sheets
YES
NO
YES

[H2] FAQ about Differin® Gel expectations

1

[H3]
How long does Differin® Gel take to work?

Differin® Gel starts working immediately, and results may be seen in as little as two weeks. It may take some time to see significant results, but with continued use, it’s been proven to work, so hang in there. In a clinical study, patients reported up to an 87% decrease in acne after 12 weeks of use.

2

[H3]
Are there any side effects?

Differin® Gel has superior tolerability compared to other retinoid acne formulations not containing adapalene. Common side effects include dryness, redness, irritation and burning/stinging. These symptoms usually peak at the 2- to 4-week mark before subsiding. Not everyone will experience these side effects, and in clinical studies, average scores were less than mild.

3

[H3]
What is retinization?

Retinization is the adjustment period in which the skin becomes acclimated with the retinoid. During this time skin may become irritated, resulting in dryness, scaling, redness and burning/stinging. Irritation usually lessens after four weeks of continued, once-daily use. It’s also important to note that some never experience retinization. This simply means Differin® Gel is still working under the surface of the skin without causing any irritation. Differin Soothing Moisturizer works to help relieve the dryness associated with retinization.

4

[H3]
When is irritation most likely to occur?

Skin irritation (redness, itching, dryness, burning) is more likely to occur in the first few weeks of use and/or if you use more than one topical acne product at a time. Avoid products containing salicylic acid, alpha hydroxy acid or glycolic acid, which may dry out your skin and worsen irritation.

5

[H3]
If I experience irritation (or signs of retinization), should I discontinue use? What can I do to minimize skin irritation?

Absolutely not. It’s a common, temporary reaction that will usually subside after about 4 weeks of use. Use of Differin® Gel should not be discontinued, but be sure to always use it just once daily. Try a gentle, non-comedogenic moisturizer, like Differin Soothing Moisturizer, to help manage irritation.The early skin irritation that sometimes occurs when using Differin® Gel is known as retinization, which is the adjustment period when your skin adapts to the retinoid. Using a gentle cleanser and moisturizer may help decrease dryness and other signs of irritation. If you experience prolonged symptoms, or if irritation becomes severe (overly bothersome), stop use and consult your physician before using the product again.Irritation may occur if using more than one topical acne product at a time. Avoid products containing harsh chemicals, salicylic acid, alpha hydroxy acid or glycolic acid, which may dry out skin and worsen irritation.

6

[H3]
How does Differin® Gel look and feel?

Differin® Gel is an oil-free and fragrance-free water-based gel that doesn’t contain alcohol. It’s light in texture and won’t leave skin feeling sticky.

[H2] FAQ About using differin

1

[H3]
How often should I use Differin® Gel?

Differin® Gel should be used only once daily and integrated as an important step into your morning or evening skincare routine. Try to apply the product at the same time each day. For best results, first wash skin with a mild (non-irritating), non-drying cleanser; apply a thin layer of Differin® Gel to clean, dry skin (full face); and follow treatment with a moisturizer. If Differin® Gel is used during the day, allow it to dry before applying sunscreen. Differin® Gel should not be used more than once a day. Applying more than directed will not provide faster or better results.

2

[H3]
Can I use Differin® Gel as a spot treatment? Why should Differin® Gel be applied to the entire face?

Differin® Gel is different. It’s highly effective, but you can’t use it like a typical over-the-counter acne product. It’s not a spot treatment and should not be used to treat a single pimple. For example, if you get acne on the face, Differin® Gel should be applied to the entire face. It’s meant for once-daily use, even when you see no signs of acne.

3

[H3]
Can I stop using Differin® Gel once my acne clears up?

For best results, it’s important to continue using Differin® Gel even after skin looks clearer to help prevent future breakouts. With continued use, Differin® Gel will continue to clear redness and inflammations caused by acne; prevent blackheads and clogged pores, and, as a result, restore the skin’s texture and tone.

4

[H3]
Is there anything I can’t do after using Differin® Gel?

Differin® Gel should not be used in conjunction with products containing alpha hydroxy, salicylic or glycolic acids, which may worsen irritation. Irritation may occur if using more than one topical acne product at a time. Do not use wax to remove unwanted hair in areas where the product has been applied. When possible, limit sun exposure, including light from tanning beds. When going outdoors, use sunscreen as labeled.

5

[H3]
Is it safe to shave while using Differin® Gel with adapalene?

Yes, you can shave. However, because irritation may occur when using adapalene, especially during the earlier stages of treatment, it’s a good idea to use shaving products that are mild and gentle. A moisturizer may be used to help alleviate dryness. Do not use wax to remove unwanted hair in areas where the product has been applied.

6

[H3]
Who should use Differin® Gel?

Differin® Gel is approved for use in people 12 years and older with mild-to-moderate acne. If you have severe acne, talk to your doctor or visit acne.com for more information.

7

[H3]
Is it okay for pregnant women to use Differin® Gel?

Differin® Gel is a safe and effective treatment. However, as with any medication, it’s a good idea to check with your doctor if you are pregnant, planning to become pregnant or breastfeeding.

[IMG: Differin 0.1% Adapalene Gel Treatment]

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[H4] Before + After
Clear results from using Differin® Gel that have the beauty community talking.

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[H1] 9 tips for keeping skin healthy
Feel good, look good. Take care of your whole self and your skin will benefit.",
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